Magnesium oxide
Drug ingredientCAS 1309-48-4
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$212M
Top sourceChina 46%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 251990 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 46%ChinaIL 13%IsraelCA 12%CanadaBR 10%BrazilJP 6%Japan
- Austria
- Germany
- Netherlands
- Czech Republic
- India
- Belgium
- Liechtenstein
- Taiwan
- Switzerland
- Pakistan
- South Korea
- Chile
EPA-registered manufacturers (19)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Amg Critical Materials Nv · NL Netherlands
Cementir Holding N V · IT Italy
Clariant International · CH Switzerland
Advanced Micronutrient Products
Agmet
Show all 19
Befesa Holding Us
Chemmasters
Clariant
Heraeus Metal Processing
Lehigh White Cement
Martin Marietta Materials
Mcwane
Mcwane Ductile New Jersey
Metallurg
Minerals Technologies
Mississippi Lime
Pilot Chemical Holdings
Shinagawa Americas
Steel Dust Recycling
Domestic parents -- activity not disclosed (8)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Albemarle
Basf
Basstech International
Heidelberg Materials Us Cement
Icl Specialty Products North America
Show all 8
Polyventive
Quadra Chemicals
Wego Chemical Group
EPA-registered importers (37)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Clariant International · CH Switzerland
Jsw Steel · IN India
Lg Chem · KR South Korea
Northern Star Resources · AU Australia
Show all 37
Ravago S A · LU Luxembourg
Rearden Holdings Eins Gmbh · DE Germany
Safic-Alcan · FR France
Sojitz · JP Japan
Acero Junction Holdings
Air Products And Chemicals
Aoc
Buckman Laboratories
Cameron Chemical
Chemspec
Ei Ceramics
Federal-Mogul V.S.P.
Haifa North America
Honeywell International (123312)
Johnson Matthey
Jost Chemical
Lg Chem America
Magnesita Refractories
Magni Industries
Metals And Additives
Northern Star (Pogo)
Ravago Holdings America
Sojitz Corporation Of America
Southern Ionics
St Marys Cement
Tateho Ozark Technical Ceramics
Tenneco Brake
The Hallstar
The Lincoln Electric
United Refining
W. R. Grace & Co. - Conn.
Welding Alloys (Usa)
29 FDA-registered drug labelers
A-S Medication Solutions
Acella Pharmaceuticals, LLC
Allegiant Health
Allegis Pharmaceuticals, LLC
Aphena Pharma Solutions - Tennessee, LLC
APNAR PHARMA LP
Avion Pharmaceuticals, LLC
Belleview Bioscience LLC
Belleview Biosciences
Blue Heron Pharmaceuticals, LLC
Bryant Ranch Prepack
CarWin Pharmaceutical Associates, LLC
DEAD SEA PERICLASE
Dead Sea Periclase Ltd
Deseret Biologicals, Inc.
Endo USA
Exeltis USA, Inc.
Ferring Pharmaceuticals Inc.
Hahnemann Laboratories, INC.
Hebei Meishen Technology Co., Ltd
Kesin Pharma
Marlex Pharmaceuticals Inc
Method Pharmaceuticals, LLC
NPG Bio Pharmaceuticals Co.,Ltd.
Oncora Pharma, LLC
PureTek Corporation
Richmond Pharmaceuticals, Inc.
Westminster Pharmaceuticals, LLC
Womens Choice Pharmaceuticals, LLC
Why It Matters
Sectors
HealthAgricultureFoodEnergyWaterElectronicsTransportationConstructionMetals & MiningPlastics & RubberTextilesPaints & CoatingsPaper & PrintingCore Chemicals
Downstream Uses
Appears in 54 drug and cosmetic product listings (FDA).
- •Magnesium Oxide
- •Dem Zero
- •Quflora Pediatric
- •Magnesia Oxydata
- •Prenatryl
- •Ventrixyl Fe
- •Vitafol Fe Plus
- •Aflora
Show all 54
- •Vitrexate
- •Venexa
- •Prenate Restore
- •Folartex
- •Folixia
- •Nutralyn
- •PNV-Omega
- •Vitranol Fe
- •Pretrate
- •Folitin-Z
- •Prenate Enhance
- •Clenpiq
- •Prenatrix
- •Multitam
- •Prenate Elite
- •Prenate Mini
- •Alzh L
- •TriStart DHA
- •Intimate
- •Multitol-M
- •Menatrol
- •Vitrexyl plus Iron
- •Ribotin-E
- •Prenate Essential
- •Folaten
- •PNV-Select
- •Connection
- •Vitrexate FE
- •Ventrixyl
- •Vitramyn
- •Vitafol Ultra
- •Mag 440
- •Nestabs ONE
- •Prenatol-M
- •Foliflex
- •Prenate DHA
- •Strovite One Caplets
- •Matronex
- •Finazol
- •Vitrexyl
- •Vitranol
- •Zintrexyl-C
- •Magnesium Oxide 400mg
- •Prometa
- •Venexa FE
- •Prenate Chewable
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 26 sectors as 20 functional roles.
- •Filler in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (80%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Inorganic Chemical Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Polymerization promoter in Rubber Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Petroleum Lubricating Oil and Grease Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Absorbent in Primary Metal ManufacturingProcessing as a reactant
- •Flux agent in All Other Basic Organic Chemical Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Primary Metal ManufacturingProcessing as a reactant
- •pH regulating agent in All Other Chemical Product and Preparation Manufacturing (1%)Processing as a reactant
- •Adsorbent in Machinery Manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Paper Manufacturing (5%)Processing as a reactant
- •Intermediate in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (1%)Processing as a reactant
- •pH regulating agent in All Other Basic Inorganic Chemical Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (2%)Processing as a reactant
- •Corrosion inhibitor in Utilities (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Chemical reaction regulator in Primary Metal Manufacturing (28%)Processing—incorporation into formulation, mixture, or reaction product
- •Chemical reaction regulator in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (7%)Processing—incorporation into article
- •Absorbent in Rubber Product ManufacturingProcessing—incorporation into article
- •Absorbent in Adhesive ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Absorbent in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Thickening agent in Plastics Product ManufacturingProcessing—incorporation into article
- •Catalyst in Petroleum Refineries (100%)Processing as a reactant
- •Adsorbent in Adhesive Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Computer and Electronic Product Manufacturing (28%)Use—non-incorporative activities
- •Catalyst in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (72%)Use—non-incorporative activities
- •Filler in Machinery ManufacturingUse—non-incorporative activities
- •Catalyst in All Other Basic Organic Chemical Manufacturing (100%)Use—non-incorporative activities
- •Adsorbent in Industrial Gas Manufacturing (100%)Use—non-incorporative activities
- •Hardener in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Hardener in Primary Metal ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Textiles, apparel, and leather manufacturing (100%)Processing as a reactant
- •Processing aids, specific to petroleum production in Petroleum Refineries (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Primary Metal ManufacturingProcessing as a reactant
- •pH regulating agent in Mining (except Oil and Gas) and support activities (100%)Processing as a reactant
- •Stabilizing agent in Primary Metal Manufacturing (100%)Processing—incorporation into article
- •Adsorbent in Petroleum Refineries (25%)Use—non-incorporative activities
- •Flavoring and nutrient in Food, beverage, and tobacco product manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Hardener in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Filler in Synthetic Rubber ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Insulators in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)Use—non-incorporative activities
- •Stabilizing agent in Plastics Product Manufacturing (100%)Processing—incorporation into article
- •Absorbent in All Other Basic Organic Chemical Manufacturing (30%)Use—non-incorporative activities
- •Absorbent in Construction (5%)Use—non-incorporative activities
- •Absorbent in Industrial Gas Manufacturing (80%)Use—non-incorporative activities
- •Flux agent in Fabricated Metal Product Manufacturing (100%)Use—non-incorporative activities
- •Catalyst in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Pigment in Transportation Equipment ManufacturingProcessing—incorporation into article
- •Catalyst in All Other Basic Inorganic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Catalyst in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.07/gSigma-Aldrich (Rush Stock)
CountryGermany
Pack$74.83 / 1 kg
Purity100.5%
Vendors6 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
5 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Sigma-Aldrich | Germany | $0.07 | 1 kg | 100.5% |
| AK Scientific Specialized | United States | $0.39 | 500 g | 95% |
| Combi-Blocks, Inc. | United States | $0.40 | 500 g | 96% |
| AK Scientific, Inc. | United States | $0.53 | 500 g | 99.5% |
| Fluorochem EU | Germany | $0.92 | 25 g | 98% |
Chemical Identity
CAS1309-48-4
PubChem CID14792
DTXSIDDTXSID9049665
FormulaMgO
Mol. Weight40.305 g/mol
SMILESO=[Mg]
Data Sources
- EPA CompTox (DSSTox) · DTXSID9049665Retrieved 2026-04-06
- PubChem · compound 14792Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Magnesium oxide (CAS 1309-48-4) https://chemicalindependence.com/chemical/1309-48-4/ EPA CompTox (DSSTox): DTXSID9049665. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9049665 PubChem: 14792. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/14792 EPA Chemical Data Reporting: 1309-48-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 1309-48-4. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 251990 for CAS 1309-48-4. Reporting year: 2024. https://usatrade.census.gov/