Bismuth hydroxide nitrate oxide (Bi5(OH)9(NO3)4O)

Drug ingredient

CAS 1304-85-4

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 1304-85-4 — 9 OH⁻ · 5 Bi³⁺ · 1 O²⁻

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$345M

Top sourceCanada 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 283429, 320649 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Zero · Imports 1.1M lb

These shares come from HS customs code 283429, 320649, which covers 71 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 25%CanadaDE 20%GermanyMX 14%MexicoJP 6%JapanCN 6%China

Colombia
Slovakia
Poland
Taiwan
Romania
Israel
Egypt
Turkey
Brazil
Switzerland
Ireland
Malaysia
Finland
Denmark
South Africa
United Arab Emirates
Cyprus
Greece
Czech Republic
Portugal
Moldova
Russia
Chile
Dominican Republic
Slovenia
Singapore
Australia
Ukraine
New Zealand
Indonesia
Hong Kong
Hungary
Peru
Pakistan
Honduras
Tunisia

EPA-registered importers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

5N Plus

Basf

Why It Matters

Sectors

HealthTransportationPaints & Coatings

Downstream Uses

Appears in 14 drug and cosmetic product listings (FDA).

•Bismuthum Subnitricum
•HPYL PLUS
•Gum Therapy
•Gastrotone
•Oral Health
•Irritable Bowel Syndrome Therapy
•D-120
•Gastropar

Show all 14

•Stomach Distress
•GI Distress
•Cal-5-Revive
•GUNA-Stomach
•Digestion
•D-119

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 1 functional role.

•Catalyst in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Catalyst in Transportation Equipment ManufacturingProcessing—incorporation into article

Chemical Identity

CAS1304-85-4

PubChem CID73415757

DTXSIDDTXSID40893872

FormulaBi5H9N4O22

Mol. Weight1461.99 g/mol

SMILES[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-2].[Bi+3].[Bi+3].[Bi+3].[Bi+3].[Bi+3]

Data Sources

EPA CompTox (DSSTox) · DTXSID40893872Retrieved 2026-04-06
PubChem · compound 73415757Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Bismuth hydroxide nitrate oxide (Bi5(OH)9(NO3)4O) (CAS 1304-85-4) https://chemicalindependence.com/chemical/1304-85-4/ EPA CompTox (DSSTox): DTXSID40893872. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID40893872 PubChem: 73415757. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/73415757 EPA Chemical Data Reporting: 1304-85-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 283429,320649 for CAS 1304-85-4. Reporting year: 2024. https://usatrade.census.gov/