1,4-Naphthoquinone

Drug ingredient

CAS 130-15-4

Companies reported imports and no US production of this drug ingredient to EPA for 2023.

US productionZero

Import value, 2024$35M

Import volume88.2K lb

Import dependency100%

Top sourceChina 49%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

1,4-Naphthoquinone · US import value by year

2013: $105M · Peak 2015: $157M · 2024: $35M · 2025: $33M

Where It Comes From

Customs basis: HS 291469 · basket

EPA reports by year

2023: US production Zero · Imports 88.2K lb
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291469, which covers 31 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 49%ChinaIN 17%IndiaJP 11%JapanNL 9%NetherlandsIT 8%Italy

Germany
Taiwan
Canada

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Aceto Us

1 FDA-registered drug labeler

Energique, Inc.

Why It Matters

Sectors

HealthMetals & Mining

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Liverex I
•Kidnex IV

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Corrosion inhibitor in Miscellaneous Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.02/gApollo Scientific US

CountryUnited Kingdom

Pack$108.00 / 5 kg

Purity97%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
Chemscene	United States	$0.14	500 g	—
ALFA AESAR	Germany	$0.14	2.5 kg	97%
MedChemExpress MCE	Sweden	$0.17	500 g	99.97%
Synthonix	United States	$0.18	500 g	95%
Sigma-Aldrich (Rush Stock)	Germany	$0.24	1 kg	96.5%
Sigma-Aldrich	Germany	$0.24	1 kg	96.5%
Ambeed, Inc.	United States	$0.60	100 g	97%
AK Scientific, Inc.	United States	$0.91	100 g	98%
Interbioscreen	Hong Kong	$24.00	10 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Molnova	China	$410.00	100 mg	99%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
Vitas M Chemical Limited	Hong Kong	$3170.00	100 mg	90%
ChemDiv, Inc.	United States	$4070.00	100 mg	90%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS130-15-4

PubChem CID8530

DTXSIDDTXSID5040704

FormulaC10H6O2

Mol. Weight158.15 g/mol

SMILESC1=CC=C2C(=O)C=CC(=O)C2=C1

Data Sources

EPA CompTox (DSSTox) · DTXSID5040704Retrieved 2026-04-06
PubChem · compound 8530Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,4-Naphthoquinone (CAS 130-15-4) https://chemicalindependence.com/chemical/130-15-4/ EPA CompTox (DSSTox): DTXSID5040704. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5040704 PubChem: 8530. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8530 EPA Chemical Data Reporting: 130-15-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 130-15-4. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291469 for CAS 130-15-4. Reporting year: 2024. https://usatrade.census.gov/