Cyproheptadine

Drug ingredient

CAS 129-03-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.3B

Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland

Taiwan
Ukraine
Sweden
Argentina
Canada
Finland
Malta
Israel
Netherlands
Denmark
United Arab Emirates
Mexico
Brunei
Slovakia
Australia
South Africa
Poland
Latvia
Lithuania
Estonia
Slovenia
Czech Republic
Croatia
Hong Kong

2 FDA-registered drug labelers

Method Pharmaceuticals, LLC

Patrin Pharma, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•cyproheptadine hydrochloride solution
•Cyproheptadine Hydrochloride

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$63.90/gA2B Chem LLC (1 week)

CountryUnited States

Pack$639.00 / 10 g

Purity98%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS (1 week)	United States	$67.50	10 g	98%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
TargetMol Chemicals	China → United States	$3115.00	200 mg	99.92%
Vitas M Chemical Limited	Hong Kong	$3170.00	100 mg	90%
MedChemExpress MCE	Sweden	$6497.70	100 mg	99.92%
Aaron Chemicals LLC	Hong Kong	$8000.00	100 mg	99.86%
Angene International Limited	United States	$8830.00	100 mg	98%
Combi-Blocks (back-ordered)	United States	$10400.00	100 mg	95%

Chemical Identity

CAS129-03-3

PubChem CID2913

DTXSIDDTXSID8022872

FormulaC21H21N

Mol. Weight287.4 g/mol

SMILESCN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1

Data Sources

PubChem · compound 2913Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Cyproheptadine (CAS 129-03-3) https://chemicalindependence.com/chemical/129-03-3/ PubChem: 2913. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/2913 FDA National Drug Code directory: CAS 129-03-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 129-03-3. Reporting year: 2024. https://usatrade.census.gov/