Docusate calcium

Drug ingredient

CAS 128-49-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 128-49-4 — 1 Ca²⁺

US productionNot reported

Import value, 2024$139M

Top sourceChina 67%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291719 · basket

These shares come from HS customs code 291719, which covers 176 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 67%ChinaCA 13%CanadaAT 4%AustriaIN 4%IndiaJP 4%Japan

Taiwan
Netherlands
Switzerland
Mexico
South Africa
Denmark
Malaysia
Ukraine
Colombia
Hong Kong
Slovakia

7 FDA-registered drug labelers

AENOVA ROMANIA S.R.L

AmerisourceBergen Drug Corp

CVS Pharmacy

Patheon Softgels Inc.

Reese Pharmaceutical Co

Rite Aid

Walgreens

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Stool Softener Laxative
•Rite Aid Stool Softener
•Stool Softener
•Preferred Stool Softener
•Good Neighbor Pharmacy Stool Softener

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$157.00/gAaron Chemicals LLC

CountryHong Kong

Pack$785.00 / 5 g

Purity95%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$158.00	5 g	97%
AstaTech (2 weeks)	United States	$206.00	5 g	95%
A2B Chem LLC (1 week)	United States	$277.00	1 g	97%
Combi-Blocks, Inc.	United States	$320.00	1 g	95%
BLD Pharmatech Ltd.	China	$390.00	1 g	97%
AA BLOCKS (1 week)	United States	$482.00	1 g	97%
MedKoo Biosciences, Inc	United States	$2600.00	250 mg	98%

Chemical Identity

CAS128-49-4

PubChem CID31407

DTXSIDDTXSID2044212

FormulaC40H74CaO14S2

Mol. Weight883.2 g/mol

SMILESCCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].[Ca+2]

Data Sources

PubChem · compound 31407Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Docusate calcium (CAS 128-49-4) https://chemicalindependence.com/chemical/128-49-4/ PubChem: 31407. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/31407 FDA National Drug Code directory: CAS 128-49-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291719 for CAS 128-49-4. Reporting year: 2024. https://usatrade.census.gov/