Sodium saccharin

Drug ingredient

CAS 128-44-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US production42.5K lb

Import value, 2024$18M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceSouth Korea 56%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292511 · narrow

EPA reports by year

2023: US production 42.5K lb · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292511, which covers 5 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

KR 56%South KoreaCN 23%ChinaIN 20%IndiaID 1%Indonesia

Panama
Spain
Malaysia
Germany

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Macdermid

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Marubeni America

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Safic-Alcan · FR France

Atotech Manufacturing

Atotech Usa

Chemspec

Why It Matters

Sectors

HealthConstructionConsumer ProductsPaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 5 functional roles.

•Plating agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Filler in Paint and Coating Manufacturing (32%)Processing—incorporation into formulation, mixture, or reaction product
•Flavoring and nutrient in Pharmaceutical and Medicine Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
•Filler in Adhesive Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
•Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.16/gAaron Chemicals LLC

CountryHong Kong

Pack$157.00 / 1 kg

Purity98%

Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

15 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.19	500 g	99%
A2B Chem LLC	United States	$0.26	500 g	98%
AK Scientific, Inc.	United States	$0.29	500 g	98%
AA BLOCKS	United States	$0.33	500 g	98%
AstaTech, Inc	United States	$0.39	100 g	95%
Fluorochem EU	Germany	$0.63	25 g	97%
Ambeed, Inc.	United States	$0.94	100 g	98%
Angene International Limited	United States	$1.31	100 g	95%
Interbioscreen	Hong Kong	$5.00	10 g	95%
Fulfilled by Molport	Latvia	$5.00	1 g	—
Combi-Blocks, Inc.	United States	$7.00	10 g	95%
TargetMol Chemicals	China → United States	$77.00	1 g	98%
ChemDiv, Inc.	United States	$4070.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	99%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS128-44-9

PubChem CID656582

DTXSIDDTXSID5021253

FormulaC7H4NNaO3S

Mol. Weight205.17 g/mol

SMILESC1=CC=C2C(=C1)C(=O)[N-]S2(=O)=O.[Na+]

Data Sources

EPA CompTox (DSSTox) · DTXSID5021253Retrieved 2026-04-06
PubChem · compound 656582Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Sodium saccharin (CAS 128-44-9) https://chemicalindependence.com/chemical/128-44-9/ EPA CompTox (DSSTox): DTXSID5021253. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5021253 PubChem: 656582. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/656582 EPA Chemical Data Reporting: 128-44-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 128-44-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292511 for CAS 128-44-9. Reporting year: 2024. https://usatrade.census.gov/