(1E)-1-[(1R)-2,6,6-Trimethylcyclohex-2-en-1-yl]pent-1-en-3-one

CAS 127-42-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$25M

Top sourceGermany 36%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291423 · basket

EPA reports by year

2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291423, which covers 17 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 36%GermanyCN 29%ChinaCH 19%SwitzerlandES 9%SpainIN 6%India

Mexico
Italy
Brazil
Slovakia
United Kingdom

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Iff Chemical Holdings

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS127-42-4

PubChem CID61071

DTXSIDDTXSID1051642

FormulaC14H22O

Mol. Weight206.32 g/mol

SMILESCCC(=O)C=CC1C(=CCCC1(C)C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID1051642Retrieved 2026-04-06
PubChem · compound 61071Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

(1E)-1-[(1R)-2,6,6-Trimethylcyclohex-2-en-1-yl]pent-1-en-3-one (CAS 127-42-4) https://chemicalindependence.com/chemical/127-42-4/ EPA CompTox (DSSTox): DTXSID1051642. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1051642 PubChem: 61071. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/61071 EPA Chemical Data Reporting: 127-42-4. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 127-42-4. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291423 for CAS 127-42-4. Reporting year: 2024. https://usatrade.census.gov/