N,N-Dimethylacetamide

CAS 127-19-5

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$371M

Top sourceChina 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292419 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292419, which covers 211 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 27%ChinaIN 18%IndiaDE 14%GermanyIT 10%ItalyGB 6%United Kingdom

Hungary
Austria
Spain
Egypt
Canada
Sweden
Ukraine
Denmark
Israel
Lithuania
Greece
Ireland
Taiwan
Uruguay
Turkey
Australia
Singapore
Latvia
Colombia

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Arclin Amines

Belle Chemical

Domestic parents -- activity not disclosed (7)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Bayer Us Holding

Eastman Chemical

Emd Holding

Kaneka North America

Sojitz Corporation Of America

Show all 7

Tedia

The Lycra

EPA-registered importers (5)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

Dupont Specialty Products Usa

Mitsubishi Gas Chemical America

Pht International

Why It Matters

Sectors

HealthAgricultureElectronicsMetals & MiningPlastics & RubberTextilesConsumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 12 sectors as 7 functional roles.

•Solvent in Organic Fiber Manufacturing (100%)Use—non-incorporative activities
•Intermediate in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant
•Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (27%)Processing—incorporation into formulation, mixture, or reaction product
•Semiconductor and photovoltaic agent in Electrical Equipment, Appliance, and Component Manufacturing (25%)Processing—incorporation into article
•Binder in Plastics Product Manufacturing (31%)Processing—incorporation into formulation, mixture, or reaction product
•Solvent in Pharmaceutical and Medicine Manufacturing (16%)Processing—incorporation into formulation, mixture, or reaction product
•Fuel agents in All Other Basic Organic Chemical Manufacturing (1%)Processing—repackaging
•Solvent in Miscellaneous Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Laboratory chemicals in ServicesNot Known or Reasonably Ascertainable
•Laboratory chemicals in Wholesale and Retail TradeNot Known or Reasonably Ascertainable
•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
•Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.01/gAaron Chemicals LLC

CountryHong Kong

Pack$6.00 / 1 kg

Purity98%

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.01	1 kg	98%
Fluorochem UK	United Kingdom	$0.04	500 g	99%
AK Scientific Specialized	United States	$0.13	500 g	98%
AK Scientific, Inc.	United States	$0.18	500 g	99.5%
A2B Chem LLC	United States	$0.19	500 g	98%
AA BLOCKS	United States	$0.20	500 g	98%
Angene International Limited	United States	$0.34	500 g	98%
Interbioscreen	Hong Kong	$10.00	10 g	95%
TargetMol Chemicals	China → United States	$48.00	1 g	99.13%
Labotest KG	Germany	$217.80	5000 mg	90%
Otava, Ltd.	Ukraine	$460.00	250 mg	90%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS127-19-5

PubChem CID31374

DTXSIDDTXSID5020499

FormulaC4H9NO

Mol. Weight87.12 g/mol

SMILESCC(=O)N(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID5020499Retrieved 2026-04-06
PubChem · compound 31374Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

N,N-Dimethylacetamide (CAS 127-19-5) https://chemicalindependence.com/chemical/127-19-5/ EPA CompTox (DSSTox): DTXSID5020499. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5020499 PubChem: 31374. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/31374 EPA Chemical Data Reporting: 127-19-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 127-19-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292419 for CAS 127-19-5. Reporting year: 2024. https://usatrade.census.gov/