Pyruvic acid

Drug ingredient

CAS 127-17-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$65M

Top sourceChina 20%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291830 · basket

These shares come from HS customs code 291830, which covers 98 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 20%ChinaIN 19%IndiaIT 19%ItalyCH 15%SwitzerlandJP 15%Japan

Netherlands
Ukraine
United Kingdom
New Zealand
Taiwan
Malaysia
Belgium
Madagascar
South Korea
Israel

3 FDA-registered drug labelers

BioActive Nutritional, Inc.

Energique, Inc.

Guna spa

Why It Matters

Sectors

Health

Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

•Lungex II
•Liverex I
•GUNA-Geriatrics
•Spleenex V
•Kidnex IV
•Spleenex VH
•Metabolism

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.04/gAaron Chemicals LLC

CountryHong Kong

Pack$18.00 / 500 g

Purity97%

Vendors25 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

24 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.04	1 kg	97%
AA BLOCKS	United States	$0.07	500 g	98%
A2B Chem LLC	United States	$0.07	500 g	98%
Chemscene	United States	$0.10	1 kg	—
Sigma-Aldrich (Rush Stock)	Germany	$0.10	25 kg	97%
Sigma-Aldrich	Germany	$0.10	25 kg	97%
Angene International Limited	United States	$0.12	500 g	98%
Ambeed, Inc.	United States	$0.12	500 g	96%
Fluorochem UK	United Kingdom	$0.15	1 kg	97%
Fluorochem EU	Germany	$0.15	1 kg	97%
Apollo Scientific UK	United Kingdom	$0.18	2.5 kg	98%
AK Scientific, Inc.	United States	$0.19	500 g	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	95%
ALFA AESAR	Germany	$0.60	100 g	98%
MedChemExpress MCE	Sweden	$3.00	50 g	99.86%
Interbioscreen	Hong Kong	$10.00	10 g	95%
Molnova	China	$74.00	500 mg	99%
Key Organics Ltd.	United Kingdom	$1960.00	100 mg	90%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	97%
Asinex	Netherlands	$6461.40	100 mg	90%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS127-17-3

PubChem CID1060

DTXSIDDTXSID2021650

FormulaC3H4O3

Mol. Weight88.06 g/mol

SMILESCC(=O)C(=O)O

Data Sources

PubChem · compound 1060Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Pyruvic acid (CAS 127-17-3) https://chemicalindependence.com/chemical/127-17-3/ PubChem: 1060. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/1060 EPA TSCA Inventory: CAS 127-17-3. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291830 for CAS 127-17-3. Reporting year: 2024. https://usatrade.census.gov/