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Hydroxyurea

Drug ingredient

CAS 127-07-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 127-07-1
US productionNot reported
Import value, 2024$191M
Top sourceSwitzerland 35%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292800 · basket

These shares come from HS customs code 292800, which covers 112 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 35%SwitzerlandIT 28%ItalyCN 12%ChinaIN 6%IndiaJP 6%Japan
23 FDA-registered drug labelers
American Health Packaging
Archimica S.p.A.
AvKARE
Coupler LLC
DARMERICA, LLC
Endo USA, Inc.
Genvion Corporation
Golden State Medical Supply, Inc.
H2-Pharma LLC
Leading Pharma, LLC
Major Pharmaceuticals
Medisca Inc.
Medunik
Nova Laboratories, Ltd.
OLON ACTIVE PHARMACEUTICAL INGREDIENTS INDIA PRIVATE LIMITED
Olon SpA
Professional Compounding Centers of America dba PCCA
Qilu Pharmaceutical Co., Ltd.
Shandong Anxin Pharmaceutical Co., Ltd.
Somerset Therapeutics, LLC
Spectrum Laboratory Products, Inc.
Teva Pharmaceuticals USA, Inc.
Waylis Therapeutics LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

  • •Hydroxyurea
  • •Siklos
  • •Hydrea
  • •Droxia
  • •Xromi
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.06/gA2B Chem LLC
CountryUnited States
Pack$59.00 / 1 kg
Purity98%
Vendors32 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

31 more vendors
VendorCountry$/gPackPurity
AA BLOCKSUnited States$0.06500 g98%
Aaron Chemicals LLCHong Kong$0.06500 g98%
Angene ChemicalChina → Hong Kong$0.07500 g98%
ChemsceneUnited States$0.08500 g—
Ambeed, Inc.United States$0.091 kg97%
AK Scientific SpecializedUnited States$0.091 kg98%
A2B Chem LLC (2 weeks)United States$0.10500 g97%
Fluorochem EUGermany$0.10500 g98%
AA BLOCKS (2 weeks)United States$0.12500 g97%
AK Scientific, Inc.United States$0.12500 g97%
Fluorochem UKUnited Kingdom$0.16100 g98%
Fulfilled by MolportLatvia$0.2025 g98%
Angene International LimitedUnited States$0.25500 g97%
AstaTech, IncUnited States$0.39100 g95%
SynthonixUnited States$0.40100 g97%
Apollo Scientific UKUnited Kingdom$2.4825 g98%
Cayman EuropeEstonia$13.7350 g95%
ALFA AESARGermany$14.1125 g98%
Apexbio Technology LLCUnited States$14.405 g99.47%
Sigma-Aldrich (Rush Stock)Germany$21.46100 g98%
Sigma-AldrichGermany$21.46100 g98%
MedChemExpress MCESweden$21.545 g99.34%
InterbioscreenHong Kong$34.0010 g95%
MolnovaChina$48.001 g99%
MedKoo Biosciences, IncUnited States$50.005 g98%
TargetMol ChemicalsChina → United States$53.001 g99.92%
ChemFacesChina$1500.0020 mg98%
Otava, Ltd.Ukraine$2060.00100 mg95%
AngeneChina → Hong Kong$4266.6730 mg98%
Vitas M Chemical LimitedHong Kong$9000.0010 mg90%
Princeton BioMolecular Research (SC)United States$10500.0010 mg90%

Chemical Identity

CAS127-07-1
PubChem CID3657
DTXSIDDTXSID6025438
FormulaCH4N2O2
Mol. Weight76.055 g/mol
SMILESC(=O)(N)NO

Data Sources

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Brief citations

Hydroxyurea (CAS 127-07-1) https://chemicalindependence.com/chemical/127-07-1/ PubChem: 3657. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3657 FDA National Drug Code directory: CAS 127-07-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292800 for CAS 127-07-1. Reporting year: 2024. https://usatrade.census.gov/