Dextromethorphan hydrobromide

Drug ingredient

CAS 125-69-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 125-69-9
1 HBr
US productionNot reported
Import value, 2024$111M
Top sourceIndia 28%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293349 · basket

These shares come from HS customs code 293349, which covers 94 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 28%IndiaCN 27%ChinaSE 12%SwedenKR 10%South KoreaGB 4%United Kingdom
305 FDA-registered drug labelers
7-ELEVEN
A-S Medication Solutions
AAA Pharmaceutical, Inc.
AARNA USA, Inc.
Acella Pharmaceuticals, LLC
Acme United
ACTIPHARMA, LLC
Advance Pharmaceutical Inc.
Advanced Generic Corporation
Advanced Rx LLC
Ahold U.S.A., Inc,
Akron Pharma Inc.
Aldama Pharmaceuticals, Inc
Allegiant Health
Allegis Pharmaceuticals, LLC
Alternative Pharmacal Corporation
AMAZON.COM SERVICES LLC
American Sales Company
AMERISOURCE BERGEN
AmerisourceBergen Drug Corp
Amneal Pharmaceuticals Co. (I) Pvt. Ltd.
Amneal Pharmaceuticals LLC
AMZ789 LLC
ANI Pharmaceuticals, Inc.
Apex Healthcare Limited
APL HEALTHCARE LIMITED
AptaPharma Inc.
Army & Air Force Exchange Service
ARMY AND AIR FORCE EXCHANGE SERVICE
Ascend Laboratories, LLC
Asclemed USA, Inc.
ATLANTIC BIOLOGICALS CORP.
Aurobindo Pharma Limited
Aurohealth LLC
Avanir Pharmaceuticals, Inc.
Axsome Therapeutics, Inc.
Bayer HealthCare LLC.
Belmora LLC
BENARD INDUSTRIES INC
Best Choice
Best Choice (Valu Merchandisers Company)
BETTER LIVING BRANDS LLC.
BI-MART
BIONPHARMA INC.
Bioventure Healthcare - FZE
BJWC
Bryant Ranch Prepack
Cabinet Health P.B.C.
CalmCo LLC
Camber Consumer Care
Camber Pharmaceuticals, Inc.
Capital Pharma
Capital Pharmaceutical, LLC
Cardinal Health
Cardinal Health (Leader) 70000
Cardinal Health 110, Inc. DBA LEADER
CARDINAL HEALTH 110, LLC. DBA LEADER
CARDINAL HEALTH 110, LLC. DBA LEADER 70000
Care One (American Sales Company)
Care One (Retail Business Services, LLC.)
Catalent Ontario Limited
Catalent Pharma Solution, LLC
Catalent Pharma Solutions, LLC
CHAIN DRUG CONSORTIUM
Chain Drug Consortium, LLC
Chain Drug Manufacturing Assn
Chain Drug Marketing Association
CHAIN DRUG MARKETING ASSOCIATION INC
Chartwell Governmental & Specialty RX, LLC
Chartwell RX, LLC
Cosette Pharmaceuticals, Inc.
Costco Wholesale Company
Cranbury Pharmaceuticals, LLC
CVS
CVS HEALTH
CVS HEALTH CORP
CVS PHARMACY
CVS PHARMACY, INC
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
Dasami Lab Private Limited
DeMoulas Market Basket
Dextrum Laboratories Inc
DISCOUNT DRUG MART
Divi's Laboratories Limited
DLC Laboratories, Inc.
Dolgencorp Inc
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)
DOLGENCORP, LLC
Domel Laboratories
DORAL PHARMAMEDICS INC dba A.G. Marin Pharmaceuticals
Dr. Reddy's Laboratories Inc.
Dr. Reddy's Labratories Inc.
DXM Pharmaceutical, Inc
DXM Pharmacuetical, Inc.
EDWARDS PHARMACEUTICALS, INC.
EFFICIENT LABORATORIES INC
ELYSIUM PHARMACEUTICALS LIMITED
Elysium Pharmaceuticals Ltd
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
Everpharm LLC
Exemed Pharmaceuticals
Eywa Pharma Inc
FAMILY DOLLAR
Family Dollar (FAMILY WELLNESS)
FAMILY DOLLAR SERVICES
FAMILY DOLLAR SERVICES INC
FOODHOLD U.S.A., LLC
FORTUNE PHARMACAL COMPANY LIMITED
Foundation Consumer Brands
Foundation Consumer Healthcare
FSA Store Inc. (Caring Mills)
GADAL Laboratories, Inc
Geiss, Destin & Dunn Inc.
Genexa
Genexa Inc.
Genomma Lab USA
Genomma Lab USA, Inc
GERI-CARE PHARMACEUTICAL CORP
GERI-CARE PHARMACEUTICALS, CORP
Gil Pharmaceutical Corp
Giltuss Pharmaceutical Corp
GM Pharmaceuticals, INC
Gobrands, Inc. (Goodnow)
Good Sense (Geiss, Destin & Dunn, Inc.)
GOODSENSE
GRANDALL DISTRIBUTING, LLC
Grimann, S.A. de C.V.
Grocery Outlet
Grocery Outlet, Inc.
Guardian Drug Company
H E B
Haleon US Holdings LLC
HARRIS TEETER
Harris Teeter, LLC
HART Health
Health Pharma USA LLC
HealthLife of USA
Hi-Tech Nutraceuticals, LLC
Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd
Humanwell PuraCap Pharmaceutical (Wuhan), Ltd.
Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd
Humco Holding Group, Inc
HY-GRO CHEMICALS PHARMTEK PVT LTD
HYVEE INC
I World Pharmaceutical Co., Ltd.
Innovida Pharmaeutique Corporation
Insight Pharmaceuticals LLC
InvaTech Pharma Solutions LLC
IPG PHARMACEUTICALS, INC.
J.C. World Bell Wholesale Co., Inc.
Janssen Cilag SpA
JHK DBA American Safety & First Aid
Jiangsu Baozong & Baoda Pharmachem Co., Ltd
Jones Healthcare Group - Packaging Services, Inc
Kenvue Brands LLC
Kenvue Canada Inc.
KESIN PHARMA CORPORATION
KinderFarms, LLC
KJD Pharma Private Limited
KRAMER LABORATORIES
KRAMER NOVIS
KROGER
KROGER COMPANY
L Perrigo Company
L.N.K. International, Inc.
LABORATORIO MAGANCEHM INTERNATIONAL SRL
LABORATORIO MAGNACHEM INTERNATIONAL SRL
Larken Laboratories, Inc.
LETCO MEDICAL, LLC
Lidl US LLC
Lil Drug Store Products, Inc
Llorens Pharmaceutical International Division
Llorens Pharmaceutical International Division, Inc.
LLORENS PHARMACEUTICALS INTERNATIONAL DIVISION
Lydia Co., Ltd.
Magno-Humphries, Inc.
Major Pharmaceuticals
Malladi Drugs & Pharmaceuticals Limited
MARC GLASSMAN, INC.
MEDGEL PRIVATE LIMITED
Medisca Inc.
MEDTECH PRODUCTS INC
MEDWISE LIFESCIENCES INC.
Meijer
MEIJER DISTRIBUTION INC
MEIJER, INC.
MENPER DISTRIBUTORS INC.
Method Pharmaceuticals
Midway Importing Inc.
Morning Star OTC
Natco Pharma USA LLC
Navajo Manufacturing Company Inc.
NuCare Pharmaceuticals, Inc.
NUVICARE LLC
Oakhurst Company
OHM LABORATORIES INC
Okendpharma, Inc.
OPMX LLC
Otsuka America Pharmaceutical, Inc
P & L Development, LLC
Padagis Israel Pharmaceuticals Ltd
Padagis US LLC
PAI Holdings, LLC dba PAI Pharma
Patheon Inc.
Patheon Softgels Inc
PD-Rx Pharmaceuticals, Inc.
Pharbest Pharmaceuticals, Inc.
PHARMACY VALUE ALLIANCE LLC
Pharmadel LLC
PIONEER LIFE SCIENCES, LLC
Poly Pharmaceuticals, Inc.
Preferred Pharmaceuticals Inc
Prestige Brands Holdings, Inc.
Procaps S.A. de C.V.
Procter & Gamble Manufactura S de RL de CV
Procter & Gamble Manufacturing Company
Prodose, Inc.
Professional Compounding Centers of America
Proficient Rx LP
PUBLIX SUPER MARKETS INC
PuraCap Pharmaceutical LLC
QIDONG DONGYUE PHARMACEUTICAL CO., LTD.
QUALITY CHOICE (Chain Drug Marketing Association)
R J General Corporation
R. A. McNeil Company
RANDOB LABS,LTD. DBA CROSSINGWELL CONSUMER HEALTH
RARITAN PHARMACEUTICALS
RARITAN PHARMACEUTICALS INC
RB Health (US)
RB Health (US) LLC
Reese Pharmaceutical Co
RELIABLE 1 LABORATORIES LLC
REMEDYREPACK INC.
RETAIL BUSINESS SERVICES , LLC
Richmond Pharmaceuticals, Inc
Rising Pharma Holdings, Inc.
RITE AID
Rite Aid Corporation
Rnv LLC
RUGBY LABORATORIES
SAFEWAY
Safeway, Inc.
SALADO SALES INC.
SAM'S WEST INC
Sato Pharmaceutical Co., Ltd.
SDA Laboratories, Inc.
Selder, S.A. de C.V.
Select Consumer Group
Shield Pharmaceuticals Corp
Sincronia Logistica, S.A. de C.V.
Socius Care, LLC
SOFTGEL HEALTHCARE PRIVATE LIMITED
Softgel Healthcare Pvt Ltd
Southern Sales & Service, Inc.
Spectrum Laboratory Products, Inc.
SPIRIT PHARMACEUTICALS,LLC
Sportpharm LLC
Srini Pharmaceuticals Private Limited
Strategic Sourcing Service, LLC
Strategic Sourcing Services
Strategic Sourcing Services LLC
Strive Pharmaceuticals Inc.
SUN PHARMACEUTICAL INDUSTRIES, INC.
SUPERVALU INC
Supriya Lifescience Limited
TARGET CORP
TARGET CORPORATION
TCB USA Corporation
THE KROGER CO
The Kroger Company
The Procter & Gamble Manufacturing Company
Thompson
TIME CAP LABORATORIES, INC.
TOP CARE (Topco Associates LLC)
TOPCARE
Topco Associates
TOPCO ASSOCIATES LLC
Ulai Health LLC
Unifirst First Aid Corporation
United Natural Foods, Inc. dba UNFI
Valu Merch
VALU MERCHANDISERS COMPANY
Velocity Pharma
VESPYR BRANDS, INC.
VIVUNT PHARMA LLC
Vovantis Laboratories Private Limited
WAL-MART STORES,INC.
Walgreen
WALGREEN CO.
WALGREEN COMPANY
WALGREENS
WALGREENS CO
Walgreens Company
Walmart
WALMART INC.
WALMART INC. (see also Equate)
Wanbury Limited
Weeks & Leo Co., Inc.
Westminster Pharmaceuticals, LLC
Wildman Business Group
WINCO FOODS, LLC
Xttrium Laboratories, Inc
YYBA CORP
Zhejiang Apeloa Kangyu Pharmaceutical Co., Ltd.
Zhejiang Bamboo Pharmaceuticals Co.,Ltd

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1157 drug and cosmetic product listings (FDA).

  • •Contac COLD and FLU
  • •BupropiDex
  • •Acetaminophen 325 mg, Dextromethorphan Hydrobromide 10 mg, Phenlyephrine Hydrochloride 5 mg softgel (DAY-TIME)
  • •Nighttime Cold and Flu
  • •Mucus Relief DM
  • •Brompheniramine Maleate, Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide
  • •Amazon Basic CARE Mucus DM
  • •basic care mucus dm
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS125-69-9
PubChem CID5464025
DTXSIDDTXSID60872346
FormulaC18H26BrNO
Mol. Weight352.3 g/mol
SMILESCN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br

Data Sources

Brief citations

Dextromethorphan hydrobromide (CAS 125-69-9) https://chemicalindependence.com/chemical/125-69-9/ PubChem: 5464025. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5464025 FDA National Drug Code directory: CAS 125-69-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293349 for CAS 125-69-9. Reporting year: 2024. https://usatrade.census.gov/