Cetylpyridinium chloride
Drug ingredientCAS 123-03-5
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$1.3B
Top sourceChina 32%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293339 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Zero · Imports 434.4K lb
These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
- Taiwan
- Ukraine
- Sweden
- Argentina
- Canada
- Finland
- Malta
- Israel
- Netherlands
- Denmark
- United Arab Emirates
- Mexico
- Brunei
- Slovakia
- Australia
- South Africa
- Poland
- Latvia
- Lithuania
- Estonia
- Slovenia
- Czech Republic
- Croatia
- Hong Kong
EPA-registered manufacturers (1)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Aurorium
EPA-registered importers (2)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Jubilant Ingrevia · IN India
Jubilant Life Sciences Usa
50 FDA-registered drug labelers
Accupac LLC
Acuseplanet Inc
Amazon.com Services LLC
American Sales Company
Applied Laboratories, Inc.
Ashtel Studios, Inc
AURORIUM LLC
Avaria Health and Beauty Corp
Better Living Brands, LLC
Church & Dwight Co., Inc.
COLGATE PALMOLIVE COMPANY
CVS Pharmacy, Inc.
Demoulas Super Markets, Inc
DISHMAN CARBOGEN AMCIS LIMITED
DOCSMEDI Co., Ltd.
DONG IL PHARMS CO.,LTD
Forward Science Technologies LLC
GURUNANDA, LLC
H E B
Haleon US Holdings LLC
LEC Custom Products, Inc
Llorens Pharmaceutical International Division
Medline Industries, LP
Meijer, Inc.
Navajo Manufacturing Company Inc.
Nice-Pak Products, LLC
Old East Main Co.
OraLabs
Perrigo Direct, Inc
Publix Super Markets, Inc.
RB Health (US) LLC
Rite Aid Corporation
Rowpar Pharmaceuticals, Inc.
Sage Products LLC
Spectrum Laboratory Products, Inc.
STEEL CITY HEALTH PRIVATE LIMITED
Target Corporation
The Kroger Co.
The Procter & Gamble Manufacturing Company
Topco Associates LLC
Twice Twice LLC
Unilab Chemicals and Pharmaceuticals Private Limited
United Natural Foods, Inc. dba UNFI
Valu Merchandisers Company
Vasu Healthcare Pvt. Ltd.
Walgreen Co.
Walmart Inc.
WinCo Foods LLC
Xiling (Zhenjiang) Medical Technology Co., Ltd.
Your Military Exchanges
Why It Matters
Sectors
HealthFoodMetals & Mining
Downstream Uses
Appears in 76 drug and cosmetic product listings (FDA).
- •Crest Deep Cleanse Germ Treatment
- •Therabreath Deep Clean Fresh Mint
- •Mint
- •Hello empower mint
- •Antiseptic
- •Orasep
- •Crest Pro Health Gum plus Bacteria Guard
- •Cetylpyridinium Chloride
Show all 76
- •Brush Buddies oral rinse - healthy gums
- •GuruNanda Healthy Gums
- •Double X Concentrated
- •Equate Healthy Gums Clean Mint Breath Oral Rinse
- •Alcohol Free Antiseptic
- •Hello Clean Mint with aloe vera
- •Hello Peace Out Plaque peace out, plaque antigingivitis
- •Multi-Action Antiseptic
- •Antiplaque solution
- •Antigingivitis/Antiplaque
- •Health
- •Equate Healthy Mouth
- •Cureforte Breath Reset
- •TheraBreath Healthy Gums
- •Therabreath Plaque Control
- •Hello Extra Minty with extra cooling
- •Crest Pro-Health Intense Clean Mint
- •Parodontax Active Gum Health Clear Mint
- •Equaline Multi-Action Antiseptic
- •Scope Icy Blast
- •Scope All Day CPC Antigingivitis/Antiplaque Mouthwash All Day
- •TheraStom
- •GuruNanda Anti-Gingivitis
- •Cool Sense Concentrated
- •Esunix Oral Bacteriostatic Liquid
- •Colgate Total 12 Hr Pro-Shield Spearmint Surge
- •Crest Gum Care
- •Mint Alcohol Free
- •Cloveden 100 times higher concentrated
- •Esunix Oral Bacteriostatic Gel
- •Colgate Total Advanced Gum Health Mouthwash
- •Parodontax Gum Strengthen and Protect
- •Alcohol Free
- •CPH Anti-bacterial Breath Mist
- •Cepacol Antibacterial
- •COOL Sense Stick Gargle
- •Colgate Total Active Prevention Peppermint
- •Parodontax Active Gum Health Mint
- •Parodontax Active Gum Health Daily Mouthwash Breath Freshener
- •Antiseptic Oral Rinse
- •Antispetic
- •CloSYS Silver Healthy Gums
- •Crest Pro Health
- •Crest Pro-Health Gum Care
- •Crest Pro-Health Advantage
- •Crest Pro-Health Bacteria Guard
- •Target UP AND UP GUM CARE
- •Colgate Total Active Prevention Spearmint
- •Colgate Total Active Prevention Gum Health
- •Hello Peace Out Plaque
- •Zestymint Antiseptic
- •twice. Oral Wellness Gum Shield
- •Up and Up Antiseptic
- •Kalaya Breath Refresh
- •PerCara Oral Health Rinse Fresh Mint
- •Brush Buddies Oral Rinse Clean Mint
- •Crest Pro-Health All Day Clean Breath
- •Colgate Total Advanced Pro-Shield Peppermint Blast
- •Crest Pro-Health Intense Fresh Mint
- •Crest Pro-Health Clinical
- •CVS Antiseptic
- •Crest Pro-Health Breath Purify and Gum Care
- •Oral B Gum Detoxify Special Care Rinse
- •Crest Scope Original
- •Crest Pro-Health Multi-Protection Refreshing Clean Mint
- •DuoCare Clinical Oral Rinse
- •Corinz
- •Oral B Plaque Defense Special Care Oral Rinse
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
- •Preservative in Miscellaneous Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.17/gAaron Chemicals LLC
CountryHong Kong
Pack$85.00 / 500 g
Purity98%
Vendors24 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
23 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.27 | 100 g | 98% |
| A2B Chem LLC | United States | $0.34 | 500 g | 97% |
| AA BLOCKS | United States | $0.42 | 500 g | 97% |
| Combi-Blocks, Inc. | United States | $0.45 | 500 g | 98% |
| BLD Pharmatech GmbH | Germany | $0.48 | 500 g | 97% |
| BLD Pharmatech Ltd. | China | $0.48 | 500 g | 97% |
| Chemscene | United States | $0.49 | 500 g | — |
| BLD Pharmatech Co., Limited | United States | $0.53 | 500 g | 97% |
| Ambeed, Inc. | United States | $0.53 | 500 g | 97% |
| AK Scientific Specialized | United States | $0.81 | 100 g | 95% |
| AK Scientific, Inc. | United States | $1.09 | 100 g | 98% |
| MedChemExpress MCE | Sweden | $7.50 | 10 g | 99.75% |
| Fulfilled by Molport | Latvia | $10.00 | 500 mg | 95% |
| AstaTech (2 weeks) | United States | $11.76 | 25 g | 95% |
| Angene International Limited | United States | $54.00 | 1 g | 95% |
| Molnova | China | $76.00 | 500 mg | 99% |
| MedKoo Biosciences, Inc | United States | $250.00 | 1 g | 98% |
| Cayman Europe | Estonia | $416.50 | 100 mg | 98% |
| Apexbio Technology LLC | United States | $1000.00 | 50 mg | 99.65% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Vitas M Chemical Limited | Hong Kong | $3170.00 | 100 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| TimTec, LLC (back-ordered) | United States | $32000.00 | 15 mg | 94% |
Chemical Identity
CAS123-03-5
PubChem CID31239
DTXSIDDTXSID6041761
FormulaC21H38ClN
Mol. Weight340 g/mol
SMILESCCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.[Cl-]
Data Sources
- EPA CompTox (DSSTox) · DTXSID6041761Retrieved 2026-04-06
- PubChem · compound 31239Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Cetylpyridinium chloride (CAS 123-03-5) https://chemicalindependence.com/chemical/123-03-5/ EPA CompTox (DSSTox): DTXSID6041761. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6041761 PubChem: 31239. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/31239 EPA Chemical Data Reporting: 123-03-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 123-03-5. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 123-03-5. Reporting year: 2024. https://usatrade.census.gov/