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Doxepin hydrochloride

Drug ingredient

CAS 1229-29-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1229-29-4
1 HCl
US productionNot reported
Import value, 2024$3.5B
Top sourceIreland 57%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
59 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Amneal Pharmaceuticals NY LLC
Aphena Pharma Solutions - Tennessee, LLC
Appco Pharma LLC
Archis Pharma LLC
Aurobindo Pharma Limited
Boswell Pharmacy Services LLC d/b/a BPS Wholesale
Bryant Ranch Prepack
Chartwell RX, LLC
Contract Pharmacal Corp.
Currax Pharmaceuticals LLC
Currax Pharmaceuticals LLC dba Cypress, Hawthorn, Macoven
Dipharma Francis Srl
Direct_Rx
Endo USA, Inc.
Epic Pharma, LLC
First Nation Group, LLC
Florida Pharmaceutical Products, LLC
Golden State Medical Supply, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Lannett Company, Inc.
Leading Pharma, LLC
LETCO MEDICAL, LLC
Lifestar Pharma LLC
Major Pharmaceuticals
Marlex Pharmaceuticals, Inc.
Medisca Inc.
Micro Labs Limited
MSN Life Sciences Private Limited
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
North Star Rx LLC
Novadoz Pharmaceuticals LLC
NuCare Pharmaceuticals,Inc.
Olon SpA
Patheon Pharmaceuticals Inc.
PD-Rx Pharmaceuticals, Inc.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS
R.L.Fine Chem Private Limited
Redpharm Drug
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Safecor Health, LLC
Spectrum Laboratory Products, Inc.
Strides Pharma Science Limited
Sun Pharmaceutical Industries, Inc.
Teva API India Private Ltd
Teva Pharmaceuticals USA, Inc.
Viona Pharmaceuticals Inc
Zydus Lifesciences Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •Doxepin hydrochloride
  • •Doxepin
  • •Prudoxin
  • •Silenor
  • •Doxepin HCL
  • •Zonalon
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$1.83/gAaron Chemicals LLC
CountryHong Kong
Pack$183.00 / 100 g
Purity99%
Vendors3 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

2 more vendors
VendorCountry$/gPackPurity
AA BLOCKSUnited States$4.03100 g98%
TargetMol ChemicalsChina → United States$27.502 g99.91%

Chemical Identity

CAS1229-29-4
PubChem CID6419921
DTXSIDDTXSID8045145
FormulaC19H22ClNO
Mol. Weight315.8 g/mol
SMILESCN(C)CCC=C1C2=CC=CC=C2COC3=CC=CC=C31.Cl

Data Sources

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Brief citations

Doxepin hydrochloride (CAS 1229-29-4) https://chemicalindependence.com/chemical/1229-29-4/ PubChem: 6419921. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6419921 FDA National Drug Code directory: CAS 1229-29-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293299 for CAS 1229-29-4. Reporting year: 2024. https://usatrade.census.gov/