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Protriptyline hydrochloride

Drug ingredient

CAS 1225-55-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1225-55-4
1 HCl
US productionNot reported
Import value, 2024$41M
Top sourceIndia 37%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292149 · basket

These shares come from HS customs code 292149, which covers 80 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 37%IndiaCN 25%ChinaDE 14%GermanyMX 9%MexicoGB 4%United Kingdom
5 FDA-registered drug labelers
Dipharma Francis Srl
Emcure Pharmaceuticals Limited
Epic Pharma, LLC
Olon SpA
Sigmapharm Laboratories, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Protriptyline Hydrochloride
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS1225-55-4
PubChem CID6603149
DTXSIDDTXSID8046951
FormulaC19H22ClN
Mol. Weight299.8 g/mol
SMILESCNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl

Data Sources

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Brief citations

Protriptyline hydrochloride (CAS 1225-55-4) https://chemicalindependence.com/chemical/1225-55-4/ PubChem: 6603149. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6603149 FDA National Drug Code directory: CAS 1225-55-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292149 for CAS 1225-55-4. Reporting year: 2024. https://usatrade.census.gov/