4-Nitrobenzoyl chloride

CAS 122-04-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$84M

Top sourceChina 63%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291639 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291639, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 63%ChinaIT 19%ItalyIN 8%IndiaDE 4%GermanyCH 3%Switzerland

Spain
Ukraine
Singapore
Turkey
Norway
Czech Republic
Taiwan
South Korea
Japan
Mexico
New Zealand
Canada
Sweden
Hong Kong
Latvia

Why It Matters

Sectors

Metals & Mining

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.18/gALFA AESAR

CountryGermany

Pack$182.40 / 1 kg

Purity98%

Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

15 more vendors

Vendor	Country	$/g	Pack	Purity
Manchester Organics	United Kingdom	$0.25	250 g	98%
Combi-Blocks, Inc.	United States	$0.32	1 kg	98%
Fluorochem EU	Germany	$0.35	500 g	98%
Fluorochem UK	United Kingdom	$0.36	500 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$0.37	500 g	98%
Sigma-Aldrich	Germany	$0.37	500 g	98%
AK Scientific Specialized	United States	$1.79	100 g	95%
AK Scientific, Inc.	United States	$2.51	100 g	98%
Key Organics Ltd.	United Kingdom	$2.96	25 g	95%
Interbioscreen	Hong Kong	$10.00	10 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Otava, Ltd.	Ukraine	$460.00	250 mg	90%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Vitas M Chemical Limited	Hong Kong	$14000.00	5 mg	90%
Princeton BioMolecular Research (SC)	United States	$18000.00	5 mg	90%

Chemical Identity

CAS122-04-3

PubChem CID8502

DTXSIDDTXSID9025742

FormulaC7H4ClNO3

Mol. Weight185.56 g/mol

SMILESC1=CC(=CC=C1C(=O)Cl)[N+](=O)[O-]

Data Sources

EPA CompTox (DSSTox) · DTXSID9025742Retrieved 2026-04-06
PubChem · compound 8502Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

4-Nitrobenzoyl chloride (CAS 122-04-3) https://chemicalindependence.com/chemical/122-04-3/ EPA CompTox (DSSTox): DTXSID9025742. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9025742 PubChem: 8502. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8502 EPA Chemical Data Reporting: 122-04-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 122-04-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291639 for CAS 122-04-3. Reporting year: 2024. https://usatrade.census.gov/