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alpelisib

Drug ingredient

CAS 1217486-61-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1217486-61-7
US productionNot reported
Import value, 2024$447M
Top sourceChina 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293410 · basket

These shares come from HS customs code 293410, which covers 83 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 31%ChinaDE 25%GermanyMX 19%MexicoJP 13%JapanIN 5%India
3 FDA-registered drug labelers
Novartis Pharma Stein AG
Novartis Pharmaceuticals Corporation
SciAnda(Changshu) Pharmaceuticals, Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Piqray
  • •Vijoice
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS1217486-61-7
PubChem CID56649450
DTXSIDDTXSID70153355
FormulaC19H22F3N5O2S
Mol. Weight441.5 g/mol
SMILESCC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F

Data Sources

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Brief citations

alpelisib (CAS 1217486-61-7) https://chemicalindependence.com/chemical/1217486-61-7/ PubChem: 56649450. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/56649450 FDA National Drug Code directory: CAS 1217486-61-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293410 for CAS 1217486-61-7. Reporting year: 2024. https://usatrade.census.gov/