Malathion

Drug ingredient

CAS 121-75-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$764M

Top sourceChina 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090, 380861, 380862, 380869 · basket

These shares come from HS customs code 293090, 380861, 380862, 380869, which covers 427 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 33%ChinaES 14%SpainCH 9%SwitzerlandIN 7%IndiaIT 7%Italy

Israel
Croatia
Brazil
Ukraine
Slovakia
United Arab Emirates
Ireland
Poland
Lithuania
Singapore
Australia
Armenia
Hong Kong
Vietnam
Czech Republic
Hungary
Greece
Russia

4 FDA-registered drug labelers

Professional Complementary Health Formulas

Sun Pharmaceutical Industries, Inc.

Suven Pharmaceuticals Limited

Taro Pharmaceuticals U.S.A., Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

•POP Detox 6045
•Malathion
•Ovide
•Bridged Ring Combination 9311

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS121-75-5

PubChem CID4004

DTXSIDDTXSID4020791

FormulaC10H19O6PS2

Mol. Weight330.4 g/mol

SMILESCCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC

Data Sources

PubChem · compound 4004Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Malathion (CAS 121-75-5) https://chemicalindependence.com/chemical/121-75-5/ PubChem: 4004. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4004 FDA National Drug Code directory: CAS 121-75-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293090,380861,380862,380869 for CAS 121-75-5. Reporting year: 2024. https://usatrade.census.gov/