Flag of the United StatesAmerican Chemical Independence

Donepezil hydrochloride

Drug ingredient

CAS 120011-70-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 120011-70-3
1 HCl
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
52 FDA-registered drug labelers
A-S Medication Solutions
ACI Healthcare USA, Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Allergan, Inc.
American Health Packaging
Amneal Pharmaceuticals NY LLC
ANI Pharmaceuticals, Inc.
Aurobindo Pharma Limited
AvKARE
Bryant Ranch Prepack
Cadila Pharmaceuticals Limited
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Cipla Ltd.
Coupler LLC
Curia Italy S.r.l.
DirectRx
Dr. Reddys Laboratories Limited
Edenbridge Pharmaceuticals LLC.
Eisai Co., Ltd.
Eisai Inc.
Eisai Manufacturing Ltd.
Golden State Medical Supply, Inc.
Hetero Drugs Limited
Hisun Pharmaceuticals USA, Inc.
Jubilant Biosys limited
Lupin Pharmaceuticals, Inc.
Macleods Pharmaceuticals Limited
Major Pharmaceuticals
NCS HealthCare of KY, LLC dba Vangard Labs
Neuland Laboratories Limited
Piramal Pharma Limited
Preferred Pharmaceuticals Inc.
Proficient Rx LP
Quallent Pharmaceuticals Health LLC
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
ScieGen Pharmaceuticals, Inc.
Solco Healthcare US, LLC
SUN PHARMACEUTICAL INDUSTRIES, INC.
Synthimed Labs Private Limited
Torrent Pharmaceuticals Limited
Unichem Laboratories Limited, India
Unichem Pharmaceuticals (USA), Inc.
Upsher-Smith Laboratories, LLC
USV Private Limited
Vitruvias Therapeutics, Inc.
Wavelength Enterprises LTD
Zhejiang Hisun Pharmaceutical Co., Ltd.
ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.
Zydus Lifesciences Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

  • •donepezil hydrochloride
  • •Aricept
  • •Donepezil
  • •Memantine and Donepezil
  • •Memantine and Donepezil Hydrochlorides Extended-release
  • •memantine hydrochloride and donepezil hydrochloride
  • •Namzaric
  • •Memantine AND Donepezil Hydrochlorides
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$1.64/gAaron Chemicals LLC
CountryHong Kong
Pack$409.00 / 250 g
Purity98%
Vendors28 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

27 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$1.65250 g98%
AA BLOCKSUnited States$2.1225 g99%
A2B Chem LLCUnited States$2.1225 g99%
Combi-Blocks, Inc.United States$2.45100 g98%
BLD Pharmatech Ltd.China$2.49100 g98%
BLD Pharmatech GmbHGermany$2.89100 g99%
AK Scientific SpecializedUnited States$2.89100 g95%
Ambeed, Inc.United States$3.0025 g98%
BLD Pharmatech Co., LimitedUnited States$3.18100 g99%
AK Scientific, Inc.United States$3.87100 g98%
Angene International LimitedUnited States$6.29100 g99%
AstaTech, IncUnited States$15.8025 g97%
A2B Chem LLC (1 week)United States$44.3625 g99%
Apexbio Technology LLCUnited States$44.805 g99.92%
AA BLOCKS (1 week)United States$47.0025 g99%
MedKoo Biosciences, IncUnited States$105.0010 g98%
MolnovaChina$388.00500 mg99%
TargetMol ChemicalsChina → United States$432.00500 mg99.89%
MedChemExpress MCESweden$513.041 g99.92%
TargetMol Chemicals EUAustria$645.00200 mg99.89%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
Axon MedchemNetherlands$3840.0050 mg99%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg97%
CliniSciences GmbHSwitzerland$7740.0025 mg98%
Sigma-Aldrich (Rush Stock)Germany$9368.4050 mg98%
Sigma-AldrichGermany$9368.4050 mg98%

Chemical Identity

CAS120011-70-3
PubChem CID5741
DTXSIDDTXSID0046698
FormulaC24H30ClNO3
Mol. Weight416 g/mol
SMILESCOC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Donepezil hydrochloride (CAS 120011-70-3) https://chemicalindependence.com/chemical/120011-70-3/ PubChem: 5741. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5741 FDA National Drug Code directory: CAS 120011-70-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 120011-70-3. Reporting year: 2024. https://usatrade.census.gov/