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Brigatinib

Drug ingredient

CAS 1197953-54-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1197953-54-0
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
4 FDA-registered drug labelers
Ajinomoto Omnichem
American Pacific Corporation
Curia New York, Inc.
Takeda Pharmaceuticals America, Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Alunbrig
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS1197953-54-0
PubChem CID68165256
DTXSIDDTXSID501027929
FormulaC29H39ClN7O2P
Mol. Weight584.1 g/mol
SMILESCN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC

Data Sources

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Brief citations

Brigatinib (CAS 1197953-54-0) https://chemicalindependence.com/chemical/1197953-54-0/ PubChem: 68165256. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/68165256 FDA National Drug Code directory: CAS 1197953-54-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 1197953-54-0. Reporting year: 2024. https://usatrade.census.gov/