phentermine hydrochloride

Drug ingredient

CAS 1197-21-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1197-21-3 — 1 HCl

US productionNot reported

Import value, 2024$4M

Top sourceGermany 95%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292146 · basket

These shares come from HS customs code 292146, which covers 9 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 95%GermanyIT 5%Italy

India
United Kingdom

37 FDA-registered drug labelers

A-S Medication Solutions

Asclemed USA, Inc.

Aurolife Pharma, LLC

Bryant Ranch Prepack

Calvin Scott & Co., Inc.

Catalent Pharma Solutions, LLC

Chartwell RX, LLC

Chemische Fabrik Berg GmbH

DIRECT RX

Dr.Reddys Laboratories Inc

Elite Laboratories, Inc.

Epic Pharma, LLC

Fagron Inc

KVK-TECH, INC.

LETCO MEDICAL, LLC

Malladi Drugs & Pharmaceuticals Limited

Martek Pharmacal Co.

Medisca Inc.

Northwind Pharmaceuticals, LLC

NuCare Pharmaceuticals,Inc.

Olon SpA

PD-Rx Pharmaceuticals, Inc.

POLYGEN PHARMACEUTICALS INC.

Prasco Laboratories

Precision Dose Inc.

Preferred Pharmaceuticals Inc.

Professional Compounding Centers of America

Professional Compounding Centers of America dba PCCA

Proficient Rx LP

Siegfried USA, LLC

Solco Healthcare U.S., LLC

Sun Pharmaceutical Industries, Inc.

SUNRISE PHARMACEUTICAL, INC.

Symed Labs Limited

TAGI Pharma, Inc.

Teva Pharmaceuticals, Inc.

Vivus LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

•Phentermine Hydrochloride
•Phentermine HCL C-IV
•Phentermine
•Phentermine HCL
•Lomaira
•Phentermine and Topiramate Extended-Release
•Qsymia
•phentermine and topiramate

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Phentermine Hydrochloride Tablet
Shortage listed since June 13, 2025

See all current drug shortages

Chemical Identity

CAS1197-21-3

PubChem CID70969

DTXSIDDTXSID20152550

FormulaC10H16ClN

Mol. Weight185.69 g/mol

SMILESCC(C)(CC1=CC=CC=C1)N.Cl

Data Sources

PubChem · compound 70969Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

phentermine hydrochloride (CAS 1197-21-3) https://chemicalindependence.com/chemical/1197-21-3/ PubChem: 70969. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/70969 FDA National Drug Code directory: CAS 1197-21-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 1197-21-3. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 292146 for CAS 1197-21-3. Reporting year: 2024. https://usatrade.census.gov/