Dabrafenib mesylate

Drug ingredient

CAS 1195768-06-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

7 FDA-registered drug labelers

MSN Laboratories Private Limited

Novartis Pharma Stein AG

Novartis Pharmaceuticals Corporation

Siegfried Barbera, SL

Sterling Pharma Solutions Limited

TAPI Czech Industries s.r.o.

VALARY LAB PRIVATE LIMITED

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Tafinlar

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$78.60/gAaron Chemicals LLC

CountryHong Kong

Pack$393.00 / 5 g

Purity99%

Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$79.20	5 g	99%
BLD Pharmatech Ltd.	China	$168.00	5 g	99%
A2B Chem LLC	United States	$171.00	1 g	99%
Combi-Blocks, Inc.	United States	$184.00	5 g	98%
AA BLOCKS	United States	$205.80	5 g	99%
BLD Pharmatech Co., Limited	United States	$240.00	1 g	99%
BLD Pharmatech GmbH	Germany	$240.00	1 g	99%
Ambeed, Inc.	United States	$240.00	1 g	99%
AstaTech, Inc	United States	$347.00	5 g	95%
Molnova	China	$428.00	500 mg	99%
TargetMol Chemicals	China → United States	$476.00	500 mg	99.82%
MedChemExpress MCE	Sweden	$525.14	1 g	99.94%
Synthonix	United States	$564.00	500 mg	99%
Cayman Europe	Estonia	$894.88	1 g	98%
Angene International Limited	United States	$1150.00	500 mg	98%
MedKoo Biosciences, Inc	United States	$1450.00	1 g	98%
Apexbio Technology LLC	United States	$1690.00	100 mg	99.78%
Angene	China → Hong Kong	$4266.67	30 mg	99%

Chemical Identity

CAS1195768-06-9

PubChem CID44516822

DTXSIDDTXSID70152500

FormulaC24H24F3N5O5S3

Mol. Weight615.7 g/mol

SMILESCC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O

Data Sources

PubChem · compound 44516822Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Dabrafenib mesylate (CAS 1195768-06-9) https://chemicalindependence.com/chemical/1195768-06-9/ PubChem: 44516822. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/44516822 FDA National Drug Code directory: CAS 1195768-06-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 1195768-06-9. Reporting year: 2024. https://usatrade.census.gov/