Phenyltoloxamine citrate

Drug ingredient

CAS 1176-08-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$197M

Top sourceChina 36%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292219 · basket

These shares come from HS customs code 292219, which covers 167 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 36%ChinaIT 15%ItalyDE 14%GermanyIN 7%IndiaHU 5%Hungary

Saudi Arabia
Lithuania
Canada
Ukraine
Israel
Singapore
Mexico
Ireland
Netherlands
Malaysia
Slovakia
Denmark
Finland
Latvia
Greece
Austria

1 FDA-registered drug labeler

Procos S.p.A.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS1176-08-5

PubChem CID298107

DTXSIDDTXSID5047790

FormulaC23H29NO8

Mol. Weight447.5 g/mol

SMILESCN(C)CCOC1=CC=CC=C1CC2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Data Sources

PubChem · compound 298107Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Phenyltoloxamine citrate (CAS 1176-08-5) https://chemicalindependence.com/chemical/1176-08-5/ PubChem: 298107. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/298107 EPA TSCA Inventory: CAS 1176-08-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292219 for CAS 1176-08-5. Reporting year: 2024. https://usatrade.census.gov/