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Duloxetine

Drug ingredient

CAS 116539-59-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 116539-59-4
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
1 FDA-registered drug labeler
Moehs BCN SL

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS116539-59-4
PubChem CID60835
DTXSIDDTXSID6048385
FormulaC18H19NOS
Mol. Weight297.4 g/mol
SMILESCNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32

Data Sources

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Brief citations

Duloxetine (CAS 116539-59-4) https://chemicalindependence.com/chemical/116539-59-4/ PubChem: 60835. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/60835 FDA National Drug Code directory: CAS 116539-59-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 116539-59-4. Reporting year: 2024. https://usatrade.census.gov/