Entacapone
Drug ingredientCAS 116314-67-1
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Top sourceNo public record
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownWhere It Comes From
EPA and Census publish no US supply data for this chemical.
23 FDA-registered drug labelers
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Aphena Pharma Solutions - Tennessee, LLC
Aurobindo Pharma Limited
AvPAK
Cohance Lifescience Limited
COHANCE LIFESCIENCES LIMITED
F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.
Hetero Labs Limited
Jubilant Biosys limited
Lannett Company, Inc.
Macleods Pharmaceuticals Limited
Major Pharmaceuticals
NCS HealthCare of KY, LLC dba Vangard Labs
Neuland Laboratories Limited
Orion Corporation, Orion Pharma
Piramal Pharma Limited
Rising Pharma Holdings, Inc.
Sandoz Inc
Sun Pharmaceutical Industries, Inc.
YiChang HEC ChangJiang Pharmaceuical Co.,Ltd.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 2 drug and cosmetic product listings (FDA).
- •Carbidopa, Levodopa, and Entacapone
- •Entacapone
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Chemical Identity
CAS116314-67-1
PubChem CID5281081
DTXSIDDTXSID5046439
FormulaC14H15N3O5
Mol. Weight305.29 g/mol
SMILESCCN(CC)C(=O)C(=CC1=CC(=C(C(=C1)O)O)[N+](=O)[O-])C#N
Data Sources
- PubChem · compound 5281081Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
Brief citations
Entacapone (CAS 116314-67-1) https://chemicalindependence.com/chemical/116314-67-1/ PubChem: 5281081. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5281081 FDA National Drug Code directory: CAS 116314-67-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/