Insulin aspart

Drug ingredient

CAS 116094-23-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$16.4B

Top sourceIreland 94%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293719 · basket

These shares come from HS customs code 293719, which covers 53 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 94%IrelandAR 4%ArgentinaCN 1%ChinaDK 1%Denmark

Switzerland
Sweden
India
Spain
Israel
Austria
Belgium
Netherlands
Italy
Hong Kong
Brazil
United Kingdom
Germany
Canada
Australia
Japan
New Zealand
Latvia
South Korea
Taiwan
Estonia
Uruguay

10 FDA-registered drug labelers

A-S Medication Solutions

Amphastar Nanjing Pharmaceuticals, Inc.

Biocon Biologics Inc.

Hefei Xinzhu Biological Technology Co., Ltd.

Novo Nordisk

Novo Nordisk A/S

Novo Nordisk Pharma, Inc.

REMEDYREPACK INC.

Sanofi-Aventis Deutschland GmbH

Sanofi-Aventis U.S. LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

•NovoLog Mix 70/30
•Insulin Aspart
•Insulin Aspart Protamine and Insulin Aspart Mix 70/30
•Novolog
•Fiasp
•Kirsty
•Merilog
•.Insulin Aspart Protamine and Insulin Aspart

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Insulin Aspart Injection
Shortage listed since July 21, 2025
to be discontinued
Insulin Aspart Protamine and Insulin Aspart Mix 70/30 Injectable Suspension
Shortage listed since July 21, 2025

See all current drug shortages

Chemical Identity

CAS116094-23-6

PubChem CID16132418

DTXSIDDTXSID10151274

FormulaC256H387N65O79S6

Mol. Weight5832 g/mol

SMILESCCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CS)C(=O)NC(CS)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(C(C)CC)C(=O)NC(CS)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)CN.CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CS)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)O)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC5=CN=CN5)NC(=O)C(CO)NC(=O)CNC(=O)C(CS)NC(=O)C(CC(C)C)NC(=O)C(CC6=CN=CN6)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC7=CC=CC=C7)N

Data Sources

PubChem · compound 16132418Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Insulin aspart (CAS 116094-23-6) https://chemicalindependence.com/chemical/116094-23-6/ PubChem: 16132418. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/16132418 FDA National Drug Code directory: CAS 116094-23-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 116094-23-6. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293719 for CAS 116094-23-6. Reporting year: 2024. https://usatrade.census.gov/