1-(Hydroxymethyl)-5,5-dimethylhydantoin

CAS 116-25-6

EPA’s 2019 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$19M

Top sourceChina 55%

EPA lists this chemical for 2019 but publishes zero or no volume for both production and imports.

Production is reported production, not a complete census of factories. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293321 · basket

EPA reports by year

2019: US production Zero · Imports Zero

These shares come from HS customs code 293321, which covers 22 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 55%ChinaTW 34%TaiwanIL 3%IsraelES 2%SpainIN 1%India

Ukraine
United Kingdom
Canada
South Korea
Germany
Latvia

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Lonza

Why It Matters

Sectors

Agriculture

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.24/gApollo Scientific UK

CountryUnited Kingdom

Pack$24.00 / 100 g

Purity97%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.33	500 g	98%
AK Scientific, Inc.	United States	$0.41	500 g	98%
A2B Chem LLC	United States	$0.44	500 g	98%
Aaron Chemicals LLC	Hong Kong	$0.58	100 g	98%
Angene Chemical	China → Hong Kong	$0.64	100 g	98%
Angene International Limited	United States	$0.69	500 g	98%
Combi-Blocks, Inc.	United States	$0.72	500 g	97%
AK Scientific Specialized	United States	$0.78	500 g	95%
AstaTech (2 weeks)	United States	$3.68	25 g	98%
Labotest KG	Germany	$217.80	5000 mg	90%
Key Organics Ltd.	United Kingdom	$2740.00	50 mg	97%
Angene	China → Hong Kong	$4266.67	30 mg	98%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%
TimTec, LLC	United States	$52000.00	5 mg	90%

Chemical Identity

CAS116-25-6

PubChem CID67000

DTXSIDDTXSID6035152

FormulaC6H10N2O3

Mol. Weight158.16 g/mol

SMILESCC1(C(=O)NC(=O)N1CO)C

Data Sources

EPA CompTox (DSSTox) · DTXSID6035152Retrieved 2026-04-06
PubChem · compound 67000Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1-(Hydroxymethyl)-5,5-dimethylhydantoin (CAS 116-25-6) https://chemicalindependence.com/chemical/116-25-6/ EPA CompTox (DSSTox): DTXSID6035152. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6035152 PubChem: 67000. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/67000 EPA Chemical Data Reporting: 116-25-6. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 116-25-6. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293321 for CAS 116-25-6. Reporting year: 2024. https://usatrade.census.gov/