Thebaine

Drug ingredient

CAS 115-37-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 115-37-7
US productionNot reported
Import value, 2024$103M
Top sourceAustralia 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293911 · basket

These shares come from HS customs code 293911, which covers 13 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
AU 31%AustraliaGB 27%United KingdomCZ 19%Czech RepublicDE 14%GermanyES 5%Spain
2 FDA-registered drug labelers
Chattem Chemicals, Inc.
Olon S.p.A.

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS115-37-7
PubChem CID5324289
DTXSIDDTXSID7046099
FormulaC19H21NO3
Mol. Weight311.4 g/mol
SMILESCN1CCC23C4C(=CC=C2C1CC5=C3C(=C(C=C5)OC)O4)OC

Data Sources

Brief citations

Thebaine (CAS 115-37-7) https://chemicalindependence.com/chemical/115-37-7/ PubChem: 5324289. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5324289 FDA National Drug Code directory: CAS 115-37-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293911 for CAS 115-37-7. Reporting year: 2024. https://usatrade.census.gov/