Docetaxel

Drug ingredient

CAS 114977-28-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$3.5B

Top sourceIreland 57%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy

United Kingdom
Japan
Germany
Spain
Israel
Canada
Brazil
Vietnam
Ukraine
New Zealand
Belgium
Mexico
Singapore
Taiwan
South Korea
Sweden
South Africa
Egypt
Indonesia
Lithuania
Finland
Hungary
Czech Republic
Hong Kong
Malaysia
Slovakia
Australia
Russia
Jordan
Latvia
Argentina
Slovenia
Malta
Poland
Denmark
Austria

20 FDA-registered drug labelers

Actavis Pharma, Inc.

Armas Pharmaceuticals Inc.

Avyxa Pharma, LLC

Baxter Healthcare Corporation

Chongqing Sintaho Pharmaceutical Co., Ltd.

Dr. Reddy's Laboratories Inc.

Fujian South Pharmaceutical Co., Ltd.

Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.

Hikma Pharmaceuticals USA Inc.

Hospira, Inc.

Jiangsu Hengrui Pharmaceuticals Co., Ltd.

Meitheal Pharmaceuticals Inc.

MSN Laboratories Private Limited

Mylan Institutional LLC

Sandoz Inc.

Sanofi-Aventis U.S. LLC

ScinoPharm Taiwan Ltd.

Shandong Anxin Pharmaceutical Co., Ltd.

Wuhan Calmland Pharmaceuticals Co., Ltd.

Yung Shin Pharmaceutical Ind. Co., Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Docivyx
•Docetaxel

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Docetaxel Injection
Shortage listed since June 24, 2025

See all current drug shortages

Chemical Identity

CAS114977-28-5

PubChem CID148124

DTXSIDDTXSID0040464

FormulaC43H53NO14

Mol. Weight807.9 g/mol

SMILESCC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Data Sources

PubChem · compound 148124Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Docetaxel (CAS 114977-28-5) https://chemicalindependence.com/chemical/114977-28-5/ PubChem: 148124. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/148124 FDA National Drug Code directory: CAS 114977-28-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 114977-28-5. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293299 for CAS 114977-28-5. Reporting year: 2024. https://usatrade.census.gov/