Trabectedin

Drug ingredient

CAS 114899-77-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7M

Top sourceIndia 45%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293980 · basket

These shares come from HS customs code 293980, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 45%IndiaCH 15%SwitzerlandCN 15%ChinaDE 10%GermanyNZ 9%New Zealand

Canada
Estonia
Spain

4 FDA-registered drug labelers

Janssen Products, LP

Jiangsu Hengrui Pharmaceuticals Co., Ltd.

MSN Laboratories Private Limited

NATCO PHARMA LIMITED

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Yondelis

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS114899-77-3

PubChem CID108150

DTXSIDDTXSID2046880

FormulaC39H43N3O11S

Mol. Weight761.8 g/mol

SMILESCC1=CC2=C(C3C4C5C6=C(C(=C7C(=C6C(N4C(C(C2)N3C)O)COC(=O)C8(CS5)C9=CC(=C(C=C9CCN8)O)OC)OCO7)C)OC(=O)C)C(=C1OC)O

Data Sources

PubChem · compound 108150Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Trabectedin (CAS 114899-77-3) https://chemicalindependence.com/chemical/114899-77-3/ PubChem: 108150. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/108150 FDA National Drug Code directory: CAS 114899-77-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293980 for CAS 114899-77-3. Reporting year: 2024. https://usatrade.census.gov/