Calcipotriene

Drug ingredient

CAS 112965-21-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$118M

Top sourceGermany 19%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290619 · basket

These shares come from HS customs code 290619, which covers 137 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 19%GermanyCH 17%SwitzerlandBR 17%BrazilIN 11%IndiaIT 10%Italy

Netherlands
Ukraine
Canada
United Kingdom
Malaysia
Australia
Indonesia
Czech Republic
Belgium

18 FDA-registered drug labelers

Anhui Haoyuan Pharmaceutical Co., Ltd. (Taodian Avenue Division)

Assia Chemical Industries Ltd - Teva Tech Site

Bryant Ranch Prepack

Cerbios-Pharma SA

CHONGQING HUAPONT SHENGCHEM PHARM. CO., INC.

Cosette Pharmaceuticals, Inc.

DARMERICA, LLC

Evereen Shanghai Biotechnology Ltd.

Formosa Laboratories, Inc.

Glenmark Pharmaceuticals Inc., USA

Glenmark Pharmaceuticals Inc.,USA

Mayne Pharma

MC2 Therapeutics Ltd

Northstar Rx LLC

Padagis Israel Pharmaceuticals Ltd

Prasco Laboratories

Sun Pharmaceutical Industries, Inc.

Taro Pharmaceuticals U.S.A., Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Calcipotriene
•Calcipotriene and Betamethasone Dipropionate
•Calcitrene
•Sorilux
•Wynzora

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS112965-21-6

PubChem CID5288783

DTXSIDDTXSID0046648

FormulaC27H40O3

Mol. Weight412.6 g/mol

SMILESCC(C=CC(C1CC1)O)C2CCC3C2(CCCC3=CC=C4CC(CC(C4=C)O)O)C

Data Sources

PubChem · compound 5288783Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Calcipotriene (CAS 112965-21-6) https://chemicalindependence.com/chemical/112965-21-6/ PubChem: 5288783. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5288783 FDA National Drug Code directory: CAS 112965-21-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 290619 for CAS 112965-21-6. Reporting year: 2024. https://usatrade.census.gov/