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Pioglitazone hydrochloride

Drug ingredient

CAS 112529-15-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 112529-15-4
1 HCl
US productionNot reported
Import value, 2024$447M
Top sourceChina 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293410 · basket

These shares come from HS customs code 293410, which covers 83 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 31%ChinaDE 25%GermanyMX 19%MexicoJP 13%JapanIN 5%India
35 FDA-registered drug labelers
A-S Medication Solutions
American Health Packaging
Aphena Pharma Solutions - Tennessee, LLC
Aurobindo Pharma Limited
AvKARE
Bryant Ranch Prepack
Chartwell RX, LLC
Cipla Ltd.
DIRECT RX
Dr. Reddy's Laboratories Limited
HETERO LABS LIMITED
Juzen Chemical Corporation
Macleods Pharmaceuticals Limited
Major Pharmaceuticals
MSN Organics Private Limited
NorthStar RxLLC
NuCare Pharmaceuticals,Inc.
Padagis Israel Pharmaceuticals Ltd
Prasco Laboratories
Preferred Pharmaceuticals, Inc.
Proficient Rx LP
QUALLENT PHARMACEUTICALS HEALTH LLC
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Synthimed Labs Private Limited
Takeda GmbH
Takeda Ireland Ltd.
Takeda Pharmaceutical Co LTD
Takeda Pharmaceutical Company Limited
Takeda Pharmaceutical Company LTD
Takeda Pharmaceuticals America, Inc.
Teva API India Limited
Teva Pharmaceuticals USA, Inc.
Torrent Pharmaceuticals Limited
USV Private Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 12 drug and cosmetic product listings (FDA).

  • •Pioglitazone Hydrochloride
  • •Pioglitazone
  • •Pioglitazone Hydrochloride and Metformin Hydrochloride
  • •Alogliptin and Pioglitazone
  • •Oseni
  • •Actoplus Met
  • •Duetact
  • •Pioglitazone HCL and Metformin HCL
Show all 12
  • •Pioglitazone and metformin hydrochloride
  • •Actos
  • •Pioglitazole and metformin hydrochloride
  • •pioglitazone and glimepiride
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS112529-15-4
PubChem CID60560
DTXSIDDTXSID3044203
FormulaC19H21ClN2O3S
Mol. Weight392.9 g/mol
SMILESCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl

Data Sources

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Brief citations

Pioglitazone hydrochloride (CAS 112529-15-4) https://chemicalindependence.com/chemical/112529-15-4/ PubChem: 60560. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/60560 FDA National Drug Code directory: CAS 112529-15-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293410 for CAS 112529-15-4. Reporting year: 2024. https://usatrade.census.gov/