Armodafinil

Drug ingredient

CAS 112111-43-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$760M

Top sourceChina 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India

Israel
Croatia
Ukraine
Slovakia
United Arab Emirates
Ireland
Poland
Lithuania
Brazil
Singapore
Australia
Armenia
Hong Kong
Vietnam
Czech Republic
Hungary
Greece
Russia

19 FDA-registered drug labelers

Apotex Corp.

Aurobindo Pharma Limited

AURORE PHARMACEUTICALS PRIVATE LIMITED

Bryant Ranch Prepack

Cephalon, LLC

DirectRx

F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.

Golden State Medical Supply, Inc.

Matrix Pharmacorp Private Limited

Mylan Pharmaceuticals Inc.

Natco Pharma USA LLC

Patheon Inc.

Piramal Pharma Limited

Preferred Pharmaceuticals Inc.

Quality Care Products LLC

Sandoz Inc

ScinoPharm Taiwan Ltd.

TAPI Croatia Industries Ltd.

Teva Pharmaceuticals USA, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Armodafinil
•Nuvigil

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS112111-43-0

PubChem CID9690109

DTXSIDDTXSID90920667

FormulaC15H15NO2S

Mol. Weight273.4 g/mol

SMILESC1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N

Data Sources

PubChem · compound 9690109Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Armodafinil (CAS 112111-43-0) https://chemicalindependence.com/chemical/112111-43-0/ PubChem: 9690109. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9690109 FDA National Drug Code directory: CAS 112111-43-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293090 for CAS 112111-43-0. Reporting year: 2024. https://usatrade.census.gov/