Triethylene glycol dimethyl ether

CAS 112-49-2

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$117M

Top sourceIndia 29%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290919 · basket

EPA reports by year

2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290919, which covers 93 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 29%IndiaCN 25%ChinaJP 20%JapanBR 6%BrazilDE 4%Germany

South Korea
Singapore
Spain
United Arab Emirates
Netherlands
Belgium
Indonesia
Poland
Mexico
Taiwan
Slovakia

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Dow Chemical

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Processing aids, specific to petroleum production in All Other Basic Organic Chemical Manufacturing (100%)Use—non-incorporative activities

Vendor Pricing

$0.02/gAaron Chemicals LLC

CountryHong Kong

Pack$8.00 / 500 g

Purity99%

Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

16 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.02	500 g	99%
A2B Chem LLC	United States	$0.04	500 g	98%
Ambeed, Inc.	United States	$0.04	1 kg	99%
AA BLOCKS	United States	$0.05	500 g	98%
Chemscene	United States	$0.05	1 kg	—
Fluorochem EU	Germany	$0.07	500 g	98%
MedChemExpress MCE	Sweden	$0.07	1 kg	—
ALFA AESAR	Germany	$0.09	2.5 kg	99%
AK Scientific Specialized	United States	$0.23	500 g	98%
AK Scientific, Inc.	United States	$0.30	500 g	99.5%
Sigma-Aldrich (Rush Stock)	Germany	$0.34	250 g	99%
Sigma-Aldrich	Germany	$0.34	250 g	99%
Angene International Limited	United States	$0.54	500 g	99.5%
AstaTech, Inc	United States	$1.04	25 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	99%

Chemical Identity

CAS112-49-2

PubChem CID8189

DTXSIDDTXSID8026224

FormulaC8H18O4

Mol. Weight178.23 g/mol

SMILESCOCCOCCOCCOC

Data Sources

EPA CompTox (DSSTox) · DTXSID8026224Retrieved 2026-04-06
PubChem · compound 8189Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Triethylene glycol dimethyl ether (CAS 112-49-2) https://chemicalindependence.com/chemical/112-49-2/ EPA CompTox (DSSTox): DTXSID8026224. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8026224 PubChem: 8189. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8189 EPA Chemical Data Reporting: 112-49-2. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 112-49-2. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290919 for CAS 112-49-2. Reporting year: 2024. https://usatrade.census.gov/