Quetiapine fumarate

Drug ingredient

CAS 111974-72-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$6.4B

Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India

Finland
Netherlands
Canada
Indonesia
Mexico
Taiwan
South Korea
Austria
Croatia
Sweden
Ukraine
Denmark
Israel
Czech Republic
New Zealand
Hong Kong
Kyrgyzstan
Australia
Portugal
South Africa
Poland
Slovenia
Brazil
Slovakia
Vietnam
Latvia
Malta
Hungary
Romania
Kenya
Belarus
Russia
Turkey
Norway

74 FDA-registered drug labelers

: Preferred Pharmaceuticals Inc.

A-S Medication Solutions

Aarti Pharmalabs Limited

Accord Healthcare Inc.

ACI Healthcare USA, Inc.

Advanced Rx of Tennessee, LLC

Advanced Rx Pharmacy of Tennessee, LLC

Alembic Pharmaceuticals Limited

AlignScience Pharma Inc.

American Health Packaging

Aphena Pharma Solutions - Tennessee, LLC

Ascend Laboratories, LLC

ASCLEMED USA INC.

AstraZeneca Pharmaceuticals LP

Aurobindo Pharma Limited

AvKARE

AvPAK

BluePoint Laboratories

Bryant Ranch Prepack

Camber Pharmaceuticals, Inc.

Cardinal Health 107, LLC

Chemeca Drugs Private Limited

Cohance Lifesciences Limited

Coupler LLC

Direct Rx

Divi's Laboratories Limited

Dr.Reddy's Laboratories Limited

F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.

Fermion Oy

Golden State Medical Supply, Inc.

H2-Pharma, LLC

Hetero Labs Limited

HIKAL LIMITED

Hikma Pharmaceuticals USA Inc.

Honour Lab Limited

Ingenus Pharmaceuticals, LLC

Intas Pharmaceuticals Limited

IOL Chemicals and Pharmaceuticals Ltd.

Ipca Laboratories Limited

Jubilant Biosys limited

Klocke Pharma-Service GmbH

Lupin Pharmaceuticals, Inc.

Macleods Pharmaceuticals Limited

Major Pharmaceuticals

Matrix Pharmacorp Private Limited

Medichem Manufacturing (Malta) Ltd.

Medichem S.A.

Moehs Cantabra SL

n.v. Ajinomoto Omnichem S.A.

NCS HealthCare of KY, LLC dba Vangard Labs

NorthStar Rx LLC

Novast Laboratories, Ltd.

NuCare Pharmaceuticals, Inc.

OLON ACTIVE PHARMACEUTICAL INGREDIENTS INDIA PRIVATE LIMITED

Optimus Drugs Private Limited

PD-Rx Pharmaceuticals, Inc.

Proficient Rx LP

Quallent Pharmaceuticals Health LLC

REMEDYREPACK INC.

Rising Pharma Holdings, Inc.

ScieGen Pharmaceuticals, Inc

Solco Healthcare US, LLC

ST. MARY'S MEDICAL PARK PHARMACY

SUN PHARMACEUTICAL INDUSTRIES, INC.

Synthimed Labs Private Limited

Teva API India Private Ltd

Teva Pharmaceuticals USA, Inc.

Unichem Laboratories Limited, India

Unichem Pharmaceuticals (USA), Inc.

Uquifa Spain

XLCare Pharmaceuticals Inc.

Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.

ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.

Zhejiang Supor Pharmaceuticals Co., Ltd

Why It Matters

Sectors

Health

Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

•Quetiapine Extended Release
•Quetiapine fumarate
•Quetiapine
•Seroquel XR
•Seroquel
•Quetiapine Fumarate ER

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1.96/gAaron Chemicals LLC

CountryHong Kong

Pack$49.00 / 25 g

Purity98%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$5.40	100 g	95%
AstaTech (2 weeks)	United States	$6.00	25 g	95%
AK Scientific Specialized	United States	$6.00	25 g	95%
AK Scientific, Inc.	United States	$8.04	25 g	98%
Apexbio Technology LLC	United States	$1200.00	100 mg	99.96%
Vitas M Chemical Limited	Hong Kong	$6114.82	10 μmol	90%
Princeton BioMolecular Research (SC)	United States	$18000.00	5 mg	90%

Chemical Identity

CAS111974-72-2

PubChem CID5281025

DTXSIDDTXSID3044201

FormulaC46H54N6O8S2

Mol. Weight883.1 g/mol

SMILESC1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=CC(=O)O)C(=O)O

Data Sources

PubChem · compound 5281025Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Quetiapine fumarate (CAS 111974-72-2) https://chemicalindependence.com/chemical/111974-72-2/ PubChem: 5281025. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5281025 FDA National Drug Code directory: CAS 111974-72-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 111974-72-2. Reporting year: 2024. https://usatrade.census.gov/