Pioglitazone

Drug ingredient

CAS 111025-46-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$447M

Top sourceChina 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293410 · basket

These shares come from HS customs code 293410, which covers 83 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaDE 25%GermanyMX 19%MexicoJP 13%JapanIN 5%India

United Kingdom
Italy
Ukraine
Spain
Netherlands
Poland
Belgium
Canada
Croatia
Bulgaria
Taiwan
Sweden
Slovakia
Slovenia

1 FDA-registered drug labeler

Solco Healthcare LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Pioglitazone

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$4.80/gCombi-Blocks, Inc.

CountryUnited States

Pack$480.00 / 100 g

Purity95%

Vendors24 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

23 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$12.71	100 g	99%
AA BLOCKS	United States	$13.42	100 g	99%
Aaron Chemicals LLC	Hong Kong	$33.36	25 g	98%
Angene Chemical	China → Hong Kong	$35.64	25 g	98%
A2B Chem LLC (1 week)	United States	$39.68	25 g	99%
AA BLOCKS (1 week)	United States	$42.00	25 g	99%
AK Scientific, Inc.	United States	$44.00	25 g	98%
BLD Pharmatech Ltd.	China	$64.00	5 g	99%
Angene International Limited	United States	$68.92	25 g	98%
BLD Pharmatech Co., Limited	United States	$70.40	5 g	99%
Ambeed, Inc.	United States	$70.40	5 g	99%
AstaTech, Inc	United States	$88.00	1 g	99%
Fluorochem UK	United Kingdom	$105.82	1 g	98%
MedKoo Biosciences, Inc	United States	$115.00	10 g	98%
BLD Pharmatech GmbH	Germany	$140.00	250 mg	99%
Apexbio Technology LLC	United States	$334.00	500 mg	99.07%
TargetMol Chemicals	China → United States	$704.00	500 mg	99.57%
Ramidus AB	Sweden	$1120.00	1 g	—
TargetMol Chemicals EU	Austria	$1430.00	100 mg	99.57%
MedChemExpress MCE	Sweden	$2226.40	100 mg	99.89%
Angene	China → Hong Kong	$2500.00	30 mg	98%
AK Scientific Specialized	United States	$3900.00	100 mg	99%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%

Chemical Identity

CAS111025-46-8

PubChem CID4829

DTXSIDDTXSID3037129

FormulaC19H20N2O3S

Mol. Weight356.4 g/mol

SMILESCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3

Data Sources

PubChem · compound 4829Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Pioglitazone (CAS 111025-46-8) https://chemicalindependence.com/chemical/111025-46-8/ PubChem: 4829. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4829 FDA National Drug Code directory: CAS 111025-46-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293410 for CAS 111025-46-8. Reporting year: 2024. https://usatrade.census.gov/