Diethylene glycol
CAS 111-46-6
U.S. production volumes are classified as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$89M
Top sourceCanada 99%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 290941 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
CA 99%Canada
- Belgium
- India
- China
- Japan
- Switzerland
- Taiwan
- South Korea
- Netherlands
- Mexico
- Germany
EPA-registered manufacturers (19)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Equate Petrochemical Co K S C C · KU KU
Indorama Netherlands Bv · NL Netherlands
Kao · JP Japan
Sasol · ZA South Africa
Brenntag
Show all 19
Complex Chemical
Dover Chemical
Dow Chemical
Formosa Plastics Corporation, U.S.A.
Gulf Coast Growth Ventures
Huntsman
Indorama Ventures Usa Holdings
Kao America
Lotte Chemical Usa
Lyondell Chemical
Meglobal Americas
Minerals Technologies
Sasol Chemicals (Usa)
Shell Petroleum
Domestic parents -- activity not disclosed (8)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Albemarle
Blachford
Clariant
Dura Chemicals
Eastman Chemical
Show all 8
Icc Industries
Polyventive
Third Coast Packaging
EPA-registered importers (24)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Cci Holding · JP Japan
Equate Petrochemical Co K S C C · KU KU
Ineos · GB United Kingdom
Patcham Fzc · AE United Arab Emirates
Shell Plc · GB United Kingdom
Show all 24
Yushiro Chemical Industry · JP Japan
Agfa
Avantor
Brenntag Lubricants
Brother International
Canon U.S.A
Cci Manufacturing Il
Helm America
Hexion
Holcim Participations (Us)
Ineos Enterprises Us Hold
Mapei
Munzing
Patcham Usa
Pennzoil-Quaker State
Recochem
Soyventis North America
Univar Solutions Usa
Yushiro Mfg. America
Why It Matters
Sectors
AgricultureEnergyConstructionMetals & MiningPlastics & RubberTextilesConsumer ProductsPaints & CoatingsPaper & PrintingCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 24 sectors as 19 functional roles.
- •Intermediate in Asphalt Paving, Roofing, and Coating Materials Manufacturing (71%)Processing—repackaging
- •Heat transferring agent in Oil and Gas Drilling, Extraction, and Support activities (13%)Processing—incorporation into formulation, mixture, or reaction product
- •Freeze-thaw additive in Paint and Coating Manufacturing (13%)Processing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Fabricated Metal Product Manufacturing (100%)Use—non-incorporative activities
- •Lubricating agent in Petroleum Lubricating Oil and Grease Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Petrochemical Manufacturing (100%)Processing as a reactant
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
- •Solvent in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Heat transferring agent in All Other Basic Inorganic Chemical ManufacturingProcessing as a reactant
- •Solvent in All Other Basic Inorganic Chemical ManufacturingProcessing as a reactant
- •Intermediate in All Other Basic Inorganic Chemical ManufacturingProcessing as a reactant
- •Emulsifier in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (34%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Paint and Coating Manufacturing (33%)Processing as a reactant
- •Intermediate in Plastics Material and Resin Manufacturing (33%)Processing as a reactant
- •Solvent in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Petrochemical Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Monomers in Plastics Material and Resin Manufacturing (90%)Processing as a reactant
- •Solvent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Wholesale and Retail Trade (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-freeze agent in Wholesale and Retail Trade (99%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-freeze agent in Petrochemical Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •CBI in CBICBI
- •Intermediate in Adhesive Manufacturing (80%)Use—non-incorporative activities
- •Intermediate in Printing Ink Manufacturing (10%)Use—non-incorporative activities
- •Surfactant (surface active agent) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation Manufacturing (90%)Processing as a reactant
- •Intermediate in Paper Manufacturing (10%)Processing as a reactant
- •Solvent in Plastics Product Manufacturing (0%)Processing—incorporation into article
- •Solvent in Not Known or Reasonably Ascertainable (100%)Processing—incorporation into article
- •Solvent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Monomers in All Other Basic Organic Chemical Manufacturing (60%)Processing as a reactant
- •Lubricating agent in All Other Basic Organic Chemical Manufacturing (60%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Wholesale and Retail TradeProcessing—incorporation into formulation, mixture, or reaction product
- •Catalyst in OtherProcessing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Petroleum Refineries (100%)Use—non-incorporative activities
- •Freeze-thaw additive in Primary Metal Manufacturing (100%)Processing—incorporation into article
- •Solvent in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Construction (100%)Processing—incorporation into article
- •Wetting agent (non-aqueous) in All Other Basic Organic Chemical Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Dehydrating agent (desiccant) in All Other Basic Organic Chemical Manufacturing (1%)Processing—repackaging
- •Anti-adhesive/cohesive in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Construction (0%)Processing—incorporation into article
- •Filler in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Hydraulic fluids in All Other Chemical Product and Preparation Manufacturing (100%)Processing—repackaging
Vendor Pricing
$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$133.00 / 25 kg
Purity99%
Vendors25 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
24 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.01 | 25 kg | 99% |
| A2B Chem LLC | United States | $0.01 | 20 kg | 98% |
| AA BLOCKS | United States | $0.01 | 20 kg | 98% |
| MedChemExpress MCE | Sweden | $0.01 | 5 kg | 99.98% |
| ALFA AESAR | Germany | $0.03 | 10 kg | 99% |
| Fluorochem UK | United Kingdom | $0.03 | 1 kg | 99% |
| Fluorochem EU | Germany | $0.03 | 1 kg | 99% |
| BLD Pharmatech Co., Limited | United States | $0.03 | 1 kg | 99% |
| BLD Pharmatech GmbH | Germany | $0.03 | 1 kg | 99% |
| BLD Pharmatech Ltd. | China | $0.03 | 1 kg | 99% |
| Ambeed, Inc. | United States | $0.03 | 1 kg | 99% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.04 | 1 kg | 99% |
| Sigma-Aldrich | Germany | $0.04 | 1 kg | 99% |
| Chemscene | United States | $0.05 | 1 kg | — |
| AK Scientific Specialized | United States | $0.10 | 500 g | 98% |
| AK Scientific, Inc. | United States | $0.14 | 500 g | 99.5% |
| Angene International Limited | United States | $0.23 | 500 g | 98% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| AstaTech (2 weeks) | United States | $48.00 | 1 g | 95% |
| HTS Biochemie Innovationen | Germany | $180.00 | 100 mg | 95% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| Otava, Ltd. | Ukraine | $2280.00 | 50 mg | 95% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 95% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 99% |
Chemical Identity
CAS111-46-6
PubChem CID8117
DTXSIDDTXSID8020462
FormulaC4H10O3
Mol. Weight106.12 g/mol
SMILESC(COCCO)O
Data Sources
- EPA CompTox (DSSTox) · DTXSID8020462Retrieved 2026-04-06
- PubChem · compound 8117Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Diethylene glycol (CAS 111-46-6) https://chemicalindependence.com/chemical/111-46-6/ EPA CompTox (DSSTox): DTXSID8020462. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8020462 PubChem: 8117. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8117 EPA Chemical Data Reporting: 111-46-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 111-46-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290941 for CAS 111-46-6. Reporting year: 2024. https://usatrade.census.gov/