squalene

Drug ingredient

CAS 111-02-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$246M

Top sourceCanada 51%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290129 · basket

These shares come from HS customs code 290129, which covers 108 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 51%CanadaZA 32%South AfricaBR 6%BrazilJP 4%JapanIT 1%Italy

Spain
Ireland
India
United Kingdom
Malaysia
Dominican Republic
Mexico
Switzerland
Australia
South Korea
Turkey
Portugal
Morocco
Guyana
Poland
Netherlands
Belgium
Slovakia
Ukraine

3 FDA-registered drug labelers

BioActive Nutritional, Inc.

Deseret Biologicals, Inc.

InLight Creation, LLC.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

•Vascuflow
•Lipotox
•E.O.L.

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.26/gAaron Chemicals LLC

CountryHong Kong

Pack$132.00 / 500 g

Purity98%

Vendors3 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

2 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.42	100 g	98%
TargetMol Chemicals	China → United States	$438.00	500 mg	99.33%

Chemical Identity

CAS111-02-4

PubChem CID638072

DTXSIDDTXSID0026044

FormulaC30H50

Mol. Weight410.7 g/mol

SMILESCC(=CCCC(=CCCC(=CCCC=C(C)CCC=C(C)CCC=C(C)C)C)C)C

Data Sources

PubChem · compound 638072Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

squalene (CAS 111-02-4) https://chemicalindependence.com/chemical/111-02-4/ PubChem: 638072. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/638072 EPA TSCA Inventory: CAS 111-02-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 290129 for CAS 111-02-4. Reporting year: 2024. https://usatrade.census.gov/