Squalane

Drug ingredient

CAS 111-01-3

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$917M

Import volume600.2K lb

Top sourceCanada 95%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290110 · basket

EPA reports by year

2023: US production Confidential · Imports 600.2K lb
2019: US production 2.9M lb · Imports Zero

These shares come from HS customs code 290110, which covers 58 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 95%CanadaDE 2%GermanyBR 1%BrazilKR 1%South Korea

China
Spain
Italy
Japan
Israel
Malaysia
United Kingdom
Austria
Portugal
India
Poland
Netherlands
Turkey
Switzerland
Belgium
Greece
Sweden

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Nikko Chemical · JP Japan

Amyris

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Clariant

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Givaudan Fragrances

4 FDA-registered drug labelers

ANUBIS COSMETICS SL

Beijing JUNGE Technology Co., Ltd.

Guangzhou Kadiya Biotechnology Co., Ltd.

Qingyuan Moksha Biotechnology Co., Ltd.

Why It Matters

Sectors

Core ChemicalsHealth

Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

•Anubis Barcelona Vital Line
•Vitamin C Oil
•Aavini Double Layer Brightening Spot Correcting Essence Oil
•Yvtyvt DARK SPOT Corrector

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Fragrance in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.16/gAaron Chemicals LLC

CountryHong Kong

Pack$164.00 / 1 kg

Purity98%

Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

16 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.20	500 g	98%
Fluorochem UK	United Kingdom	$0.28	1 kg	92%
Combi-Blocks, Inc.	United States	$0.30	500 g	95%
Fluorochem EU	Germany	$0.32	500 g	97%
A2B Chem LLC	United States	$0.36	500 g	95%
ALFA AESAR	Germany	$0.37	500 g	98%
AA BLOCKS	United States	$0.41	500 g	95%
Sigma-Aldrich (Rush Stock)	Germany	$0.51	500 g	96%
Sigma-Aldrich	Germany	$0.51	500 g	96%
AstaTech (2 weeks)	United States	$0.83	500 g	95%
MedChemExpress MCE	Sweden	$16.21	10 g	99.4%
Angene International Limited	United States	$28.50	10 g	98%
TargetMol Chemicals	China → United States	$31.00	1 g	98%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Molnova	China	$3600.00	25 mg	99%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS111-01-3

PubChem CID8089

DTXSIDDTXSID0046513

FormulaC30H62

Mol. Weight422.8 g/mol

SMILESCC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID0046513Retrieved 2026-04-06
PubChem · compound 8089Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Core Chemicals

Brief citations

Squalane (CAS 111-01-3) https://chemicalindependence.com/chemical/111-01-3/ EPA CompTox (DSSTox): DTXSID0046513. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0046513 PubChem: 8089. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8089 EPA Chemical Data Reporting: 111-01-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 111-01-3. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 290110 for CAS 111-01-3. Reporting year: 2024. https://usatrade.census.gov/