meclizine dihydrochloride

Drug ingredient

CAS 1104-22-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1104-22-9 — 2 HCl

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

1 FDA-registered drug labeler

Medtech Products Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Dramamine
•Dramamine Less Drowsy

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.72/gCombi-Blocks, Inc.

CountryUnited States

Pack$360.00 / 500 g

Purity98%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$0.77	500 g	98%
AA BLOCKS	United States	$0.81	500 g	98%
AstaTech, Inc	United States	$1.19	100 g	98%
Angene International Limited	United States	$2.54	100 g	98%
Aaron Chemicals LLC	Hong Kong	$2.93	100 g	98%
Angene Chemical	China → Hong Kong	$3.15	100 g	98%
Fluorochem UK	United Kingdom	$5.86	10 g	95%
AK Scientific, Inc.	United States	$9.36	25 g	98%
Fulfilled by Molport	Latvia	$16.00	250 mg	98%
MedChemExpress MCE	Sweden	$23.96	5 g	99.95%
MedKoo Biosciences, Inc	United States	$47.50	20 g	98%
Molnova	China	$450.00	100 mg	99%
TargetMol Chemicals	China → United States	$500.00	100 mg	99.79%
Apexbio Technology LLC	United States	$530.00	100 mg	99.9%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%
Cayman Europe	Estonia	$15850.80	50 mg	98%

Chemical Identity

CAS1104-22-9

PubChem CID64713

DTXSIDDTXSID9045348

FormulaC25H29Cl3N2

Mol. Weight463.9 g/mol

SMILESCC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl

Data Sources

PubChem · compound 64713Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

meclizine dihydrochloride (CAS 1104-22-9) https://chemicalindependence.com/chemical/1104-22-9/ PubChem: 64713. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/64713 EPA TSCA Inventory: CAS 1104-22-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 1104-22-9. Reporting year: 2024. https://usatrade.census.gov/