Piperazine

CAS 110-85-0

U.S. production volumes are classified as confidential business information.

Molecular structure of 110-85-0
US productionCBI
Import value, 2024$7.6B
Top sourceIreland 61%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
EPA-registered manufacturers (1)
Dow Chemical
Domestic parents -- activity not disclosed (1)
Huntsman
EPA-registered importers (4)
Basf Se · DE Germany
Tosoh · JP Japan
Basf
Tosoh America

Why It Matters

Sectors
ConstructionMetals & MiningCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 5 sectors as 2 functional roles.

  • •CBI in CBICBI
  • •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
  • •Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Fabricated Metal Product Manufacturing (0%)Processing as a reactant
  • •Intermediate in Adhesive ManufacturingProcessing as a reactant

Vendor Pricing

$0.08/gA2B Chem LLC
CountryUnited States
Pack$40.00 / 500 g
Purity98%
Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS110-85-0
PubChem CID4837
DTXSIDDTXSID1021164
FormulaC4H10N2
Mol. Weight86.14 g/mol
SMILESC1CNCCN1

Data Sources

Brief citations

Piperazine (CAS 110-85-0) https://chemicalindependence.com/chemical/110-85-0/ EPA CompTox (DSSTox): DTXSID1021164. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1021164 PubChem: 4837. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/4837 EPA Chemical Data Reporting: 110-85-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 110-85-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293359 for CAS 110-85-0. Reporting year: 2024. https://usatrade.census.gov/