1,4-Butanediol

CAS 110-63-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$82M

Top sourceGermany 18%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290539 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290539, which covers 48 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 18%GermanyKR 16%South KoreaBR 11%BrazilTW 8%TaiwanMX 7%Mexico

Canada
Liechtenstein
Israel
Ireland
Portugal
Ukraine
Singapore

EPA-registered manufacturers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Ashland

Basf

Lyondell Chemical

Domestic parents -- activity not disclosed (8)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Aceto Us

American River Brokerage

Cellmark Basic Materials

Huntsman

Palmer Holland

Show all 8

Soyventis North America

The Lycra

Tri-Iso

EPA-registered importers (10)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Era Polymers International Usa Pty · AU Australia

Lg Chem · KR South Korea

Daxx

Dow Chemical

Dupont Specialty Products Usa

Show all 10

Era Polymers

Everchem

Lanxess

Lg Chem America

Penn A Kem

Why It Matters

Sectors

EnergyConstructionMetals & MiningPlastics & RubberConsumer ProductsPaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 11 sectors as 7 functional roles.

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
•Intermediate in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
•Intermediate in Plastics Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Wholesale and Retail Trade (10%)Processing—repackaging
•Intermediate in Paint and Coating Manufacturing (18%)Processing as a reactant
•Intermediate in Petrochemical Manufacturing (43%)Processing as a reactant
•Surface modifier in Miscellaneous Manufacturing (100%)Processing as a reactant
•Hardener in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing as a reactant
•Wrinkle resisting agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Plasticizer in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Adhesive ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Intermediate in Oil and Gas Drilling, Extraction, and Support activitiesProcessing—incorporation into formulation, mixture, or reaction product
•Intermediate in Asphalt Paving, Roofing, and Coating Materials ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Solvent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Monomers in Plastics Product Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS110-63-4

PubChem CID8064

DTXSIDDTXSID2024666

FormulaC4H10O2

Mol. Weight90.12 g/mol

SMILESC(CCO)CO

Data Sources

EPA CompTox (DSSTox) · DTXSID2024666Retrieved 2026-04-06
PubChem · compound 8064Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,4-Butanediol (CAS 110-63-4) https://chemicalindependence.com/chemical/110-63-4/ EPA CompTox (DSSTox): DTXSID2024666. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2024666 PubChem: 8064. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/8064 EPA Chemical Data Reporting: 110-63-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 110-63-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290539 for CAS 110-63-4. Reporting year: 2024. https://usatrade.census.gov/