2E,4E-Hexadienoic acid

Drug ingredient

CAS 110-44-1

EPA’s 2023 records show zero U.S. production for this drug ingredient.

US productionZero

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceNo public record

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023.

Where It Comes From

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Zero · Imports 129.3K lb

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Brenntag

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Brenntag · DE Germany

Brenntag Northeast

Why It Matters

Sectors

HealthFood

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Organic Acid Combination 9305
•Anubis Barcelona

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS110-44-1

PubChem CID643460

DTXSIDDTXSID3021277

FormulaC6H8O2

Mol. Weight112.13 g/mol

SMILESCC=CC=CC(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID3021277Retrieved 2026-04-06
PubChem · compound 643460Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07

← Back to Dashboard ← Back to Health

Brief citations

2E,4E-Hexadienoic acid (CAS 110-44-1) https://chemicalindependence.com/chemical/110-44-1/ EPA CompTox (DSSTox): DTXSID3021277. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021277 PubChem: 643460. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/643460 EPA Chemical Data Reporting: 110-44-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/