Toluene

Drug ingredient

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 108-88-3
US ProductionCBI
Import Value$465M
Top SourceSouth Korea 53%

The EPA did not publish how much of this chemical companies made or imported, or marked that amount confidential. Without that volume, ACID cannot calculate import dependency.

Where It Comes From

Customs basis: HS 270720, 290230 · exact

Source Countries
KR 53%South KoreaTW 22%TaiwanJP 4%JapanBR 4%BrazilDE 4%Germany
EPA-registered manufacturers (33)
Arlanxeo Holding Bv · NL Netherlands
Basf Se · DE Germany
Ineos · IM Isle of Man
Total Se · FR France
Americas Styrenics
Show all 33
Arlanxeo Usa
Basf
Brainerd Cemical
Chalmette Refining
Chevron
Citgo Holding
Citgo Holdings Inc, Lemont Refinery
Delek Us Holdings
Deltech
Dynachem
ExxonMobil
Husky Energy
Ineos Styrolution America
Koch Industries
Lyondell Chemical
Marathon Petroleum
Momentive Performance Materials
New Erie
Pbf Energy
Pbf Holding
Pes Ultimate Holdings
Phillips 66
Seymour Of Sycamore
Shell
Shell Chemical
Solvchem
Total Petrochemicals & Refining Usa
Westlake Petrochemicals
EPA-registered importers (53)
Basf Se · DE Germany
Bayer Ag · DE Germany
Covestro Ag · DE Germany
Dksh Holding Ag · CH Switzerland
Kansai Paint · JP Japan
Show all 53
Litasco Sa · CH Switzerland
Miki & · JP Japan
Shell · GB United Kingdom
Sika Ag · CH Switzerland
Total Se · FR France
3M
Aalborz Chemical
Akzo Nobel Coatings
Allnex Usa
Avery Dennison
Basf
Bayer Us Holding
Colonial Group
Covestro
Dksh North America
Evonik
ExxonMobil
George E. Warren
Giant Cement Holding
Gunvor Usa
Helmitin
Henkel
Ies Downstream
Innospec
Itw Evercoat
Lanxess
Lukoil Pan Americas
Marubeni America
Mie
Miki Sangyo (Usa)
Ppg Industries
Quaker Chemical
Ricoh Electronics
Shell Trading (Us)
Shin Etsu Silicones Of America
Sika
Solvay
Sopus
Stahl Usa
Tartan Oil
The Dow Chemical
The Sherwin Williams
Total Holdings Usa
Total Petrochemicals & Refining Usa
Trafigura Trading
Tricon International
Us Paint
World Fuel Services
3 FDA-registered drug labelers
Deseret Biologicals, Inc.
Energique, Inc.
Professional Complementary Health Formulas

Why It Matters

Sectors
Plastics & RubberPaints & CoatingsElectronicsTransportationPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningTextilesAgricultureConstruction
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Household Antigens
  • •Pollutox
  • •Solvent/Small Ring Combination 9317
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 28 sectors as 29 functional roles.

  • •Solvents (which become part of product formulation or mixture) in Miscellaneous Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvents (which become part of product formulation or mixture) in Adhesive Manufacturing (50%)Use—non-incorporative activities
  • •Solvents (which become part of product formulation or mixture) in Transportation Equipment Manufacturing (0%)Use—non-incorporative activities
  • •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
  • •Solvents (which become part of product formulation or mixture) in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Paint additives and coating additives not described by other categories in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fuels and fuel additives in Petroleum Refineries (80%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesives and sealant chemicals in All Other Basic Organic Chemical Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvents (for cleaning or degreasing) in All Other Basic Organic Chemical Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvents (which become part of product formulation or mixture) in Synthetic Rubber Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesives and sealant chemicals in Paper Manufacturing (100%)Use—non-incorporative activities
  • •Intermediate in All Other Chemical Product and Preparation ManufacturingProcessing as a reactant
  • •Paint additives and coating additives not described by other categories in Paint and Coating Manufacturing (0%)Processing—incorporation into article
  • •Surface modifier in Fabricated Metal Product Manufacturing (0%)Processing—incorporation into article
  • •Solvent in Transportation Equipment Manufacturing (0%)Processing—incorporation into article
  • •Defoamer in Asphalt Paving, Roofing, and Coating Materials Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvent in Plastics Material and Resin Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Opacifer in Paint and Coating Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvent in Paint and Coating Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Wetting agent (non-aqueous) in Paint and Coating Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fuel agents in All other Petroleum and Coal Products Manufacturing (0%)Use—non-incorporative activities
  • •Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant
  • •Solvent in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvents (which become part of product formulation or mixture) in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Solvent in Agriculture, Forestry, Fishing and HuntingProcessing as a reactant
  • •Intermediate in Petroleum Refineries (100%)Processing as a reactant
  • •Fuels and fuel additives in Wholesale and Retail Trade (3%)Processing—repackaging
  • •Solvents (which become part of product formulation or mixture) in Wholesale and Retail Trade (17%)Processing—repackaging
  • •Fuels and fuel additives in Petrochemical Manufacturing (58%)Processing as a reactant
  • •Anti-adhesive/cohesive in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Lubricating agent in Petroleum Refineries (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Monomers in Paint and Coating Manufacturing (10%)Processing as a reactant
  • •Fuel agents in Other (90%)Processing—incorporation into formulation, mixture, or reaction product
  • •Catalyst in Primary Metal Manufacturing (100%)Processing as a reactant
  • •Adhesives and sealant chemicals in All Other Chemical Product and Preparation Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surface active agents in All Other Chemical Product and Preparation Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Viscosity adjustors in All Other Chemical Product and Preparation Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Paint additives and coating additives not described by other categories in All Other Chemical Product and Preparation Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Wholesale and Retail Trade (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fuel agents in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fuels and fuel additives in Services (100%)Processing—repackaging
  • •Adhesives and sealant chemicals in Adhesive Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Photosensitive chemicals in Petroleum Refineries (16%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Plastics Product Manufacturing (100%)Processing as a reactant
  • •Anti-adhesive agents in Rubber Product Manufacturing (33%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesives and sealant chemicals in Other (34%)Processing—incorporation into formulation, mixture, or reaction product
  • •Laboratory chemicals in Other (90%)Processing—incorporation into formulation, mixture, or reaction product
  • •Plasticizer in Plastics Material and Resin Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Corrosion inhibitors and anti-scaling agents in Paint and Coating Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvent in Adhesive Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activities (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesion/cohesion promoter in Synthetic Rubber Manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
  • •Lubricants and lubricant additives in Synthetic Rubber Manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
  • •Solvents (which become part of product formulation or mixture) in All Other Basic Organic Chemical Manufacturing (99%)Use—non-incorporative activities
  • •Solvents (which become part of product formulation or mixture) in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
  • •Solvent in Furniture and Related Product ManufacturingProcessing—incorporation into article
  • •Solvent in ConstructionProcessing—incorporation into article
  • •Solvent in Not Known or Reasonably Ascertainable (0%)Processing—incorporation into article
  • •Fuel agents in Petroleum RefineriesProcessing—incorporation into formulation, mixture, or reaction product
  • •Fuel in Petroleum Refineries (30%)Processing—incorporation into formulation, mixture, or reaction product
  • •Sealant (barrier) in Transportation Equipment ManufacturingProcessing—incorporation into article
  • •Adhesion/cohesion promoter in Electrical Equipment, Appliance, and Component ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Diluent in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Adhesion/cohesion promoter in ConstructionProcessing—incorporation into formulation, mixture, or reaction product
  • •Sealant (barrier) in ConstructionProcessing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS108-88-3
PubChem CID1140
DTXSIDDTXSID7021360
FormulaC7H8
Mol. Weight92.14 g/mol
SMILESCC1=CC=CC=C1

Data Sources

DTXSID70213602026-04-06

https://doi.org/10.23645/epacomptox.5588566

Archive: data/sources/comptox/dsstox_identifiers.csv

11402026-04-06

https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/1140/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON

Archive: data/sources/pubchem_properties/1140.json

108-88-32026-04-24

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr.csv

CAS 108-88-32026-04-07

https://open.fda.gov/data/ndc/

Archive: data/sources/fda/ndc/ndc.json

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