Isopropyl ether

CAS 108-20-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$117M

Import volumeZero

Top sourceIndia 29%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290919 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290919, which covers 93 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 29%IndiaCN 25%ChinaJP 20%JapanBR 6%BrazilDE 4%Germany

South Korea
Singapore
Spain
United Arab Emirates
Netherlands
Belgium
Indonesia
Poland
Mexico
Taiwan
Slovakia

Domestic parents -- activity not disclosed (3)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

ExxonMobil

Geocycle

Shell Petroleum

Why It Matters

Sectors

HealthEnergyConstructionPlastics & RubberCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 5 sectors as 4 functional roles.

•Fuel agents in Petroleum Refineries (100%)Processing as a reactant
•Intermediate in Petrochemical Manufacturing (4%)Processing as a reactant
•Refrigerants in All Other Chemical Product and Preparation Manufacturing (1%)Use—non-incorporative activities
•Refrigerants in Plastics Material and Resin Manufacturing (2%)Use—non-incorporative activities
•Fuel in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)Processing—repackaging

Vendor Pricing

$217.80/gLabotest KG

CountryGermany

Pack$1089.00 / 5000 mg

Purity90%

Vendors1 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS108-20-3

PubChem CID7914

DTXSIDDTXSID4021890

FormulaC6H14O

Mol. Weight102.17 g/mol

SMILESCC(C)OC(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID4021890Retrieved 2026-04-06
PubChem · compound 7914Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Isopropyl ether (CAS 108-20-3) https://chemicalindependence.com/chemical/108-20-3/ EPA CompTox (DSSTox): DTXSID4021890. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4021890 PubChem: 7914. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/7914 EPA Chemical Data Reporting: 108-20-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 108-20-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290919 for CAS 108-20-3. Reporting year: 2024. https://usatrade.census.gov/