Tetradecamethylhexasiloxane

CAS 107-52-8

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$537M

Import volumeZero

Top sourceChina 39%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293190 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Zero

These shares come from HS customs code 293190, which covers 378 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 39%ChinaDE 17%GermanyIT 9%ItalyIN 7%IndiaJP 7%Japan

Ireland
Netherlands
Switzerland
Monaco
Ukraine
Spain
Mexico
Poland
Indonesia
Armenia
Israel
Sweden
Australia
Czech Republic
Hungary
Brunei
Hong Kong
Brazil
Thailand
Argentina
Finland
Austria
Latvia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Dow Chemical

Why It Matters

Sectors

Metals & MiningCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Chemical Product and Preparation Manufacturing (20%)Processing—repackaging

Vendor Pricing

$2.09/gAaron Chemicals LLC

CountryHong Kong

Pack$1047.00 / 500 g

Purity97%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$2.11	500 g	97%
A2B Chem LLC	United States	$6.00	25 g	97%
Combi-Blocks, Inc.	United States	$6.40	100 g	97%
AA BLOCKS	United States	$6.64	25 g	97%
Chemscene	United States	$8.36	25 g	—
BLD Pharmatech Ltd.	China	$8.39	100 g	97%
Ambeed, Inc.	United States	$8.39	100 g	97%
AstaTech, Inc	United States	$8.40	25 g	95%
BLD Pharmatech Co., Limited	United States	$8.40	25 g	97%
BLD Pharmatech GmbH	Germany	$8.40	25 g	97%
Angene International Limited	United States	$15.72	25 g	95%
Synthonix	United States	$19.00	1 g	95%
Key Organics Ltd.	United Kingdom	$1424.00	250 mg	95%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS107-52-8

PubChem CID7875

DTXSIDDTXSID3059349

FormulaC14H42O5Si6

Mol. Weight458.99 g/mol

SMILESC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID3059349Retrieved 2026-04-06
PubChem · compound 7875Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Tetradecamethylhexasiloxane (CAS 107-52-8) https://chemicalindependence.com/chemical/107-52-8/ EPA CompTox (DSSTox): DTXSID3059349. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3059349 PubChem: 7875. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/7875 EPA Chemical Data Reporting: 107-52-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 107-52-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293190 for CAS 107-52-8. Reporting year: 2024. https://usatrade.census.gov/