Betaine

Drug ingredient

CAS 107-43-7

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$108M

Top sourceChina 14%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292390 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292390, which covers 130 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 14%ChinaGB 13%United KingdomDE 11%GermanyIN 10%IndiaTW 10%Taiwan

Israel
Indonesia
Sweden
Turkey
United Arab Emirates
Malaysia
Singapore
Lithuania
Brazil
Hong Kong
Australia
Belgium
Ukraine

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

International Flavors And Fragrances

11 FDA-registered drug labelers

AMINO GmbH

ANUBIS COSMETICS SL

Beijing JUNGE Technology Co., Ltd.

Cosette Pharmaceuticals, Inc.

Eton Pharmaceuticals, Inc.

Guna spa

Jaymac Pharmaceuticals

Jaymac Pharmaceuticals, LLC

NATURECELL CO., LTD.

NURAY CHEMICALS PRIVATE LIMITED

Recordati Rare Diseases

Why It Matters

Sectors

HealthAgriculturePaper & PrintingCore Chemicals

Downstream Uses

Appears in 10 drug and cosmetic product listings (FDA).

•Betaine Anhydrous
•Yvtyvt Microdermabrasion Facial Scrub
•GUNA-Awareness
•Cystadane
•EnBrace HR
•PaxLyte
•Yvtyvt Copper Peptides Facial Serum
•Dr.Jucre Rebirth Activating Toner

Show all 10

•Anubis Barcelona Total Hydrating
•Betaine

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Anti-freeze agent in All Other Chemical Product and Preparation Manufacturing (60%)Processing—incorporation into formulation, mixture, or reaction product
•Solvent in Printing and Related Support Activities (100%)Use—non-incorporative activities

Chemical Identity

CAS107-43-7

PubChem CID247

DTXSIDDTXSID8022666

FormulaC5H11NO2

Mol. Weight117.15 g/mol

SMILESC[N+](C)(C)CC(=O)[O-]

Data Sources

EPA CompTox (DSSTox) · DTXSID8022666Retrieved 2026-04-06
PubChem · compound 247Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Betaine (CAS 107-43-7) https://chemicalindependence.com/chemical/107-43-7/ EPA CompTox (DSSTox): DTXSID8022666. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8022666 PubChem: 247. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/247 EPA Chemical Data Reporting: 107-43-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 107-43-7. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292390 for CAS 107-43-7. Reporting year: 2024. https://usatrade.census.gov/