Hydroxyacetonitrile

CAS 107-16-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$281M

Import volumeZero

Top sourceChina 31%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292690 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Zero

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Dow Chemical

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$3.34/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$83.44 / 25 g

PurityNot recorded

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$3.34	25 g	—

Chemical Identity

CAS107-16-4

PubChem CID7857

DTXSIDDTXSID3025417

FormulaC2H3NO

Mol. Weight57.05 g/mol

SMILESC(C#N)O

Data Sources

EPA CompTox (DSSTox) · DTXSID3025417Retrieved 2026-04-06
PubChem · compound 7857Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Hydroxyacetonitrile (CAS 107-16-4) https://chemicalindependence.com/chemical/107-16-4/ EPA CompTox (DSSTox): DTXSID3025417. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3025417 PubChem: 7857. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/7857 EPA Chemical Data Reporting: 107-16-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 107-16-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292690 for CAS 107-16-4. Reporting year: 2024. https://usatrade.census.gov/