valproate sodium
Drug ingredientActive ShortageCAS 1069-66-5
This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 291590 · basket
These shares come from HS customs code 291590, which covers 588 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Singapore
- Austria
- United Kingdom
- Philippines
- Canada
- Hungary
- Turkey
- Ukraine
- Israel
- Denmark
- Czech Republic
- Slovakia
- Norway
- Poland
- Hong Kong
- South Africa
- Russia
11 FDA-registered drug labelers
Why It Matters
Appears in 2 drug and cosmetic product listings (FDA).
- •Divalproex Sodium
- •Valproate Sodium
- Current shortage
Valproate Sodium Injection
Shortage listed since December 30, 2020
Manufacturer reports: 1 available
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
27 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Combi-Blocks, Inc. | United States | $0.33 | 500 g | 97% |
| Aaron Chemicals LLC | Hong Kong | $0.33 | 500 g | 98% |
| Angene Chemical | China → Hong Kong | $0.34 | 500 g | 98% |
| AA BLOCKS | United States | $0.37 | 500 g | 97% |
| BLD Pharmatech GmbH | Germany | $0.39 | 500 g | 97% |
| BLD Pharmatech Ltd. | China | $0.39 | 500 g | 97% |
| BLD Pharmatech Co., Limited | United States | $0.55 | 100 g | 97% |
| Ambeed, Inc. | United States | $0.55 | 100 g | 97% |
| AK Scientific Specialized | United States | $0.81 | 100 g | 95% |
| Fulfilled by Molport | Latvia | $1.00 | 5 g | 98% |
| Fluorochem EU | Germany | $1.02 | 25 g | 97% |
| AstaTech, Inc | United States | $1.49 | 100 g | 97% |
| AK Scientific, Inc. | United States | $1.85 | 100 g | 98% |
| Cayman Europe | Estonia | $3.08 | 100 g | 95% |
| Angene International Limited | United States | $3.20 | 100 g | 98% |
| MedChemExpress MCE | Sweden | $4.02 | 25 g | 99.65% |
| Sigma-Aldrich (Rush Stock) | Germany | $6.59 | 100 g | 98% |
| Sigma-Aldrich | Germany | $6.59 | 100 g | 98% |
| Apexbio Technology LLC | United States | $13.20 | 10 g | 98.46% |
| MedKoo Biosciences, Inc | United States | $14.00 | 25 g | 98% |
| CliniSciences GmbH | Switzerland | $32.25 | 1 g | 99% |
| Molnova | China | $45.00 | 1 g | 99% |
| TargetMol Chemicals | China → United States | $50.00 | 1 g | 99.78% |
| Axon Medchem | Netherlands | $600.00 | 100 mg | 98% |
| Otava, Ltd. | Ukraine | $2724.00 | 50 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| Key Organics Ltd. | United Kingdom | $8500.00 | 10 mg | 90% |
Chemical Identity
Data Sources
- PubChem · compound 16760703Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA Drug ShortagesRetrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
valproate sodium (CAS 1069-66-5) https://chemicalindependence.com/chemical/1069-66-5/ PubChem: 16760703. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/16760703 FDA National Drug Code directory: CAS 1069-66-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 1069-66-5. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 291590 for CAS 1069-66-5. Reporting year: 2024. https://usatrade.census.gov/