Adapalene
Drug ingredientCAS 106685-40-9
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 291899 · basket
These shares come from HS customs code 291899, which covers 139 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Austria
- Hungary
- South Korea
- Taiwan
- Czech Republic
- Mexico
- Spain
- Ukraine
- Estonia
- Australia
- Israel
- Singapore
- Slovakia
- Russia
54 FDA-registered drug labelers
Why It Matters
Appears in 17 drug and cosmetic product listings (FDA).
- •Adapalene
- •Adapalene Gel
- •Adapalene and Benzoyl Peroxide
- •epiduo forte
- •Adapalene Gel USP, 0.3%
- •Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5%
- •Effaclar
- •Differin
Show all 17
- •PanOxyl
- •ACNE Treatment
- •Proactiv MD Adapalene Acne Treatment
- •Epiduo
- •Curist Acne Relief
- •Adapalene Gel 0.1%
- •Cabtreo
- •Neutrogena Adapalene 0.1% Acne Treatment
- •Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatment
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
21 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $5.77 | 100 g | 99% |
| A2B Chem LLC | United States | $12.36 | 25 g | 95% |
| AA BLOCKS | United States | $13.76 | 25 g | 99% |
| BLD Pharmatech Co., Limited | United States | $17.40 | 25 g | 99% |
| BLD Pharmatech GmbH | Germany | $17.40 | 25 g | 99% |
| BLD Pharmatech Ltd. | China | $17.40 | 25 g | 99% |
| Ambeed, Inc. | United States | $17.40 | 25 g | 99% |
| AK Scientific Specialized | United States | $19.40 | 25 g | 95% |
| AK Scientific, Inc. | United States | $27.16 | 25 g | 98% |
| Angene International Limited | United States | $43.08 | 25 g | 98% |
| TargetMol Chemicals | China → United States | $193.00 | 1 g | 99.88% |
| MedKoo Biosciences, Inc | United States | $250.00 | 5 g | 98% |
| TargetMol Chemicals EU | Austria | $258.00 | 500 mg | 99.88% |
| Molnova | China | $340.00 | 500 mg | 99% |
| MedChemExpress MCE | Sweden | $399.30 | 500 mg | 99.94% |
| Cayman Europe | Estonia | $605.71 | 1 g | 98% |
| Apexbio Technology LLC | United States | $880.00 | 100 mg | 99.91% |
| Otava, Ltd. | Ukraine | $2724.00 | 50 mg | 90% |
| Life Chemicals Inc. | Ukraine → Canada | $3100.00 | 100 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 99% |
| Key Organics Ltd. | United Kingdom | $8500.00 | 10 mg | 97% |
Chemical Identity
Data Sources
- PubChem · compound 60164Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Adapalene (CAS 106685-40-9) https://chemicalindependence.com/chemical/106685-40-9/ PubChem: 60164. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/60164 FDA National Drug Code directory: CAS 106685-40-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291899 for CAS 106685-40-9. Reporting year: 2024. https://usatrade.census.gov/