1,4-Dimethylpiperazine

CAS 106-58-1

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$7.6B

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceIreland 61%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Huntsman

Why It Matters

Sectors

Plastics & Rubber

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Catalyst in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.21/gA2B Chem LLC

CountryUnited States

Pack$105.00 / 500 g

Purity98%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
Apollo Scientific US	United Kingdom	$0.23	1 kg	98%
AA BLOCKS	United States	$0.27	500 g	98%
Manchester Organics	United Kingdom	$0.44	250 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$0.63	100 g	98%
Sigma-Aldrich	Germany	$0.63	100 g	98%
ALFA AESAR	Germany	$0.73	100 g	98%
Combi-Blocks, Inc.	United States	$1.20	100 g	98%
Key Organics Ltd.	United Kingdom	$2740.00	50 mg	95%

Chemical Identity

CAS106-58-1

PubChem CID7818

DTXSIDDTXSID8051544

FormulaC6H14N2

Mol. Weight114.19 g/mol

SMILESCN1CCN(CC1)C

Data Sources

EPA CompTox (DSSTox) · DTXSID8051544Retrieved 2026-04-06
PubChem · compound 7818Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,4-Dimethylpiperazine (CAS 106-58-1) https://chemicalindependence.com/chemical/106-58-1/ EPA CompTox (DSSTox): DTXSID8051544. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8051544 PubChem: 7818. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/7818 EPA Chemical Data Reporting: 106-58-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 106-58-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293359 for CAS 106-58-1. Reporting year: 2024. https://usatrade.census.gov/